Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366625 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HSD17B10POLBKDM4ELMNA | |
| SCHEMBL20215642 | 0.87 | ALDH1A1 (0.41) | ALDH1A1HSD17B10POLBKDM4ELMNA | |
| SCHEMBL22540867 | 0.84 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL22540870 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1107373 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HSD17B10KDM4ELMNAMEN1 | |
| SCHEMBL2606679 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HSD17B10KDM4ELMNAMEN1 | |
| SCHEMBL11617824 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HSD17B10POLBKDM4ELMNA | |
| SCHEMBL20215636 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HSD17B10POLBKDM4ELMNA | |
| SCHEMBL4472838 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HSD17B10POLBKDM4ELMNA | |
| SCHEMBL18409005 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HSD17B10POLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874453-A | Butylphthalide impurity compound, preparation method and application thereof | 广东隆赋药业股份有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-110320293-B | Method for determining residual solvent in phthalide compound | 弘和制药有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-110221009-B | Method for measuring butylphthalide related substances by HPLC | 北京澳合药物研究院有限公司 | 2020-04-17 | — | — | CN | claimed |
| CN-110108818-B | High performance liquid chromatography for high performance separation detection of phthalide derivatives and application thereof | 北京澳合药物研究院有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-110320293-A | A kind of method of residual solvent in measurement phthalide analog compound | 北京澳合药物研究院有限公司 | 2019-10-11 | — | — | CN | claimed |
| CN-110221009-A | A kind of HPLC measurement method of the butylphenyl phthaleine in relation to substance | 北京澳合药物研究院有限公司 | 2019-09-10 | — | — | CN | claimed |
| CN-110108818-A | A kind of high performance liquid chromatography and its application efficiently separating detection phthalide derivant | 北京澳合药物研究院有限公司 | 2019-08-09 | — | — | CN | claimed |
| CN-101735185-B | Racemization method for optically active 3-butyl phthalide | ZHONGQI PHARMACEUTICAL TECHNOLOGY SHIJIAZHUANG CO LTD CSPC PHARMACEUTICAL GROUP LTD | 2012-01-25 | — | — | CN | claimed |
| CN-101735185-A | Racemization method for optically active 3-butyl phthalide | ZHONGQI PHARMACEUTICAL TECHNOLOGY SHIJIAZHUANG CO LTD | 2010-06-16 | — | — | CN | claimed |
| CN-1209356-C | Method for splitting antipode of 3-butylbenzene phthalein | DALIAN CHEMICAL PHYSICS INST (CN) | 2005-07-06 | — | — | CN | claimed |
| CN-1539835-A | Method for splitting antipode of 3-butylbenzene phthalein | 中国科学院大连化学物理研究所 | 2004-10-27 | — | — | CN | claimed |
| US-12616730-B2 | Topical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of skin ulcer and the use thereof | MEDIHELPLINE CO., LTD (KR) | 2026-05-05 | — | — | US | disclosed |
| CN-118393015-A | Detection method of butylphthalide related substances | 广东隆赋药业股份有限公司 | 2024-07-26 | — | — | CN | disclosed |
| US-11814352-B2 | Salts formed by 2-(1-acyloxy-n-pentyl) benzoic acid and basic amino acid or aminoguanidine, and preparation method and application thereof | JIANGSU KANION PHARMACEUTICAL CO., LTD. (CN) | 2023-11-14 | — | — | US | disclosed |
| CN-116874453-A | Butylphthalide impurity compound, preparation method and application thereof | 广东隆赋药业股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| EP-1539205-A1 | METHOD FOR THE PREPARATION OF PHYTOPROGESTOGENIC EXTRACTS FROM RHIZOMA LIGUSTICUM CHUANXIONG AND USES THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2005-06-15 | — | — | EP | disclosed |
| CN-1539835-A | Method for splitting antipode of 3-butylbenzene phthalein | 中国科学院大连化学物理研究所 | 2004-10-27 | — | — | CN | disclosed |
| WO-2004017983-A1 | METHOD FOR THE PREPARATION OF PHYTOPROGESTOGENIC EXTRACTS FROM RHIZOMA LIGUSTICUM CHUANXIONG AND USES THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-03-04 | — | — | WO | disclosed |
| CN-1136209-C | Process for preparing optically active 3-n-butyl phenylphthaleine | 中国医学科学院药物研究所 | 2004-01-28 | — | — | CN | disclosed |
| CN-1283621-A | Process for preparing optically active 3-n-butyl phenylphthaleine | INST OF MEDICINAL MATERIALS CH (CN) | 2001-02-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814352-B2 | Salts formed by 2-(1-acyloxy-n-pentyl) benzoic acid and basic amino acid or aminoguanidine, and preparation method and application thereof | KCNB1, KCNMB1, KCNAB1 | ALDH1A1 3520/4885HSD17B10 1671/4885POLB 471/4885 |
| US-12616730-B2 | Topical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of skin ulcer and the use thereof | CUTA, VEGFA, MMP8 | ALDH1A1 905/4885HSD17B10 3652/4885POLB 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.