Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606679 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EGAAHSD17B10MEN1 | |
| SCHEMBL4472838 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAHSD17B10MEN1 | |
| SCHEMBL18409005 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAHSD17B10MEN1 | |
| SCHEMBL28981497 | 0.84 | AKT1 (0.40) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL30366625 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL4195577 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL7938874 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL11381183 | 0.79 | POLB (0.43) | ALDH1A1GAAKMT2ACDC25BMAPT | |
| SCHEMBL20215642 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10LMNAMAPT | |
| SCHEMBL13202103 | 0.78 | MEN1 (0.33) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115932126-A | Detection method for measuring racemization-3-n-butylphthalide related substances by HPLC | 河北菲尼斯生物技术有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115901976-A | Detection method for measuring 3-butyl-1 (3H) -isobenzofuranone related substances by adopting HPLC | 河北菲尼斯生物技术有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115932126-B | Detection method for measuring racemization-3-n-butylphthalide related substances by HPLC | 河北菲尼斯生物技术有限公司 | 2025-06-06 | — | — | CN | disclosed |
| US-11834413-B2 | Antiplatelet drugs and uses thereof | SHANGHAI CUREGENE PHARMACEUTICAL CO LTD. (CN) | 2023-12-05 | — | — | US | disclosed |
| WO-2023214059-A1 | DIPHENYLPYRAZINE COMPOUNDS AS PRODRUGS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-11-09 | — | — | WO | disclosed |
| US-20230287004-A1 | SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES AND PRODRUGS THEREOF | SHIONOGI & CO., LTD. (JP) | 2023-09-14 | — | — | US | disclosed |
| EP-4219508-A1 | SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVE AND PRODRUG THEREOF | Shionogi & Co., Ltd (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-11639353-B2 | Cyclobutanes- and azetidine-containing mono and spirocyclic compounds as αV integrin inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-05-02 | — | — | US | disclosed |
| CN-115932126-A | Detection method for measuring racemization-3-n-butylphthalide related substances by HPLC | 河北菲尼斯生物技术有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115932126-A | Detection method for measuring racemization-3-n-butylphthalide related substances by HPLC | 河北菲尼斯生物技术有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115901976-A | Detection method for measuring 3-butyl-1 (3H) -isobenzofuranone related substances by adopting HPLC | 河北菲尼斯生物技术有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-7273881-B2 | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-09-25 | — | — | US | disclosed |
| US-7273881-B2 | Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-09-25 | — | — | US | disclosed |
| US-7253283-B2 | Tricyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-07 | — | — | US | disclosed |
| US-7241780-B2 | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method | BRISTOLS-MYERS SQUIBB COMPANY (US) | 2007-07-10 | — | — | US | disclosed |
| US-20070129400-A1 | Modulators of glucocorticoid receptor, AP-1, and/or NF-kB activity, and use thereof | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-07 | — | — | US | disclosed |
| US-20070129400-A1 | Modulators of glucocorticoid receptor, AP-1, and/or NF-kB activity, and use thereof | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-07 | — | — | US | disclosed |
| US-20070015797-A1 | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method | CHENG PETER T | 2007-01-18 | — | — | US | disclosed |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| US-20060264457-A1 | Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods | BRISTOL-MYERS SQUIBB COMPANY | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129400-A1 | Modulators of glucocorticoid receptor, AP-1, and/or NF-kB activity, and use thereof | NR0B1, NR3C1, NFKB2 | ALDH1A1 3765/4885KDM4E 2756/4885GAA 4315/4885 |
| US-20060264457-A1 | Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods | DPP4, DPP9, DPP3 | ALDH1A1 799/4885KDM4E 821/4885GAA 92/4885 |
| US-20230287004-A1 | SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES AND PRODRUGS THEREOF | C3AR1, NR4A1, HAVCR2 | ALDH1A1 1319/4885KDM4E 1325/4885GAA 4535/4885 |
| US-11834413-B2 | Antiplatelet drugs and uses thereof | PFKP, GP6, PF4 | ALDH1A1 734/4885KDM4E 4730/4885GAA 384/4885 |
| US-20070004700-A1 | 2-Thioethenyl substituted carbapenem derivatives | MTAP, BLVRB, BPGM | ALDH1A1 1182/4885KDM4E 2518/4885GAA 2012/4885 |
| US-11639353-B2 | Cyclobutanes- and azetidine-containing mono and spirocyclic compounds as αV integrin inhibitors | ITGB1, ITGB2, ITGA1 | ALDH1A1 1029/4885KDM4E 2185/4885GAA 2542/4885 |
| US-20070015797-A1 | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method | GPR119, LIPC, ACACA | ALDH1A1 1055/4885KDM4E 2164/4885GAA 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.