Sugi Predict

Sugi Predict / Compounds / SCHEMBL4196339

SCHEMBL4196339

SCHEMBL4196339

Oc1ccccc1[C](c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 7/20 0.54
▸ KDM4E B2RXH2 7/20 0.54
▸ SMN1; SMN2 Q16637 4/20 0.54
▸ ALDH1A1 P00352 4/20 0.54
▸ CA12 O43570 2/20 0.54
▸ CA2 P00918 2/20 0.54
▸ CA4 P22748 2/20 0.54
▸ CA14 Q9ULX7 2/20 0.54
▸ CA1 P00915 1/20 0.54
▸ HMGB1 P09429 1/20 0.54
▸ CA6 P23280 1/20 0.54
▸ CA7 P43166 1/20 0.54
▸ CA9 Q16790 1/20 0.54
▸ NAPRT Q6XQN6 1/20 0.54
▸ MAPT P10636 4/20 0.50
▸ CYP3A4 P08684 2/20 0.50
▸ HSD17B10 Q99714 4/20 0.46
▸ TSHR P16473 2/20 0.46
▸ GSTA1 P08263 1/20 0.46
▸ LMNA P02545 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2494549 0.83 HPGD (0.57) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL8471103 0.78 TP53 (0.53) HPGDKDM4ESMN1; SMN2ALDH1A1CA2
SCHEMBL21685 0.77 HPGD (0.52) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL1357094 0.77 HPGD (0.52) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL7124543 0.77 HPGD (0.52) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL50746 0.75 HPGD (0.50) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL36215 0.75 LIG1 (0.76) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL22129808 0.75 LIG1 (0.76) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL3072365 0.75 HPGD (0.50) HPGDKDM4ESMN1; SMN2ALDH1A1CA12
SCHEMBL2113883 0.75 HPGD (0.50) HPGDKDM4ESMN1; SMN2ALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4291244-A1 CELL-PENETRATING PEPTIDE CONJUGATES AND METHODS OF THEIR USE Oxford University Innovation Limited (GB) 2023-12-20 — — EP disclosed
WO-2023196499-A1 SUBSTRATE CLEAVAGE FOR NUCLEIC ACID SYNTHESIS Twist Bioscience Corporation (US) 2023-10-12 — — WO disclosed
CN-114044896-B Uniform sequence-defined polyurethanes and their use as molecular markers 国立科学研究中心 2023-08-08 — — CN disclosed
US-11359054-B2 Uniform sequence-defined polyurethanes and uses thereof as molecular labels CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-06-14 — — US disclosed
US-20220125934-A1 LINKERS UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2022-04-28 — — US disclosed
EP-3455279-B1 UNIFORM SEQUENCE-DEFINED POLYURETHANES AND USES THEREOF AS MOLECULAR LABELS CENTRE NAT RECH SCIENT (FR) 2022-04-13 — — EP disclosed
CN-114044896-A Polyurethane with uniform sequence definition and application thereof as molecular marker 国立科学研究中心 2022-02-15 — — CN disclosed
CN-109153782-B Polyurethane with uniform sequence definition and application thereof as molecular marker 国立科学研究中心 2021-12-17 — — CN disclosed
EP-3890783-A1 LINKERS Oxford University Innovation Limited (GB) 2021-10-13 — — EP disclosed
CN-113453723-A Joint 牛津大学科技创新有限公司 2021-09-28 — — CN disclosed
EP-3243857-A1 UNIFORM SEQUENCE-DEFINED POLYURETHANES AND USES THEREOF AS MOLECULAR LABELS Centre National de la Recherche Scientifique - CNRS - (FR) 2017-11-15 — — EP disclosed
EP-1536844-B1 PREPARATION OF M(CO)3-COMPLEXES BY SOLID PHASE TECHNIQUES VIA METAL ASSISTED CLEAVAGE FROM THE SOLID SUPPORT UNIV ZUERICH (CH) 2009-03-04 — — EP disclosed
US-7427260-B2 Efficient methods for solid phase synthesis using trityl chloride resins MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2008-09-23 — — US disclosed
US-20060165594-A1 Preparation of m(co)3-complexes by solid phase techniques via metal assisted cleavage from the solid support UNIVERSITY OF ZURICH (CH) 2006-07-27 — — US disclosed
EP-1536844-A2 PREPARATION OF M(CO)3-COMPLEXES BY SOLID PHASE TECHNIQUES VIA METAL ASSISTED CLEAVAGE FROM THE SOLID SUPPORT UNIVERSITY OF ZURICH (CH) 2005-06-08 — — EP disclosed
US-20040096904-A1 Efficient methods for solid phase synthesis using trityl chloride resins MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2004-05-20 — — US disclosed
WO-2004022105-A2 PREPARATION OF M(CO)3-COMPLEXES BY SOLID PHASE TECHNIQUES VIA METAL ASSISTED CLEAVAGE FROM THE SOLID SUPPORT UNIVERSITY OF ZURICH (CH) 2004-03-18 — — WO disclosed
WO-2002083606-A1 A LINKER SYSTEM FOR THE SYNTHESIS AND SCREENING OF COMBINATORIAL LIBRARIES OF POLYAMINE DERIVATIVES ON WATER COMPATIBLE SUPPORTS UNIVERSITY OF ALBERTA (CA) 2002-10-24 — — WO disclosed
WO-2002079278-A1 EFFICIENT METHODS FOR SOLID PHASE SYNTHESIS USING TRITYL CHLORIDE RESINS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2002-10-10 — — WO disclosed
WO-2000026262-A2 FUNCTIONALIZED POLYMERIC SUBSTRATES FOR BINDING MOLECULAR MOIETIES MITOKOR (US) 2000-05-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060165594-A1 Preparation of m(co)3-complexes by solid phase techniques via metal assisted cleavage from the solid support C9, KIT, MCM3 HPGD 3396/4885KDM4E 1865/4885SMN1; SMN2 679/4885
US-20220125934-A1 LINKERS GABRA5, GABRA2, GABRG2 HPGD 1517/4885KDM4E 2767/4885SMN1; SMN2 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.