Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215863 | 0.79 | CYP3A4 (0.43) | SIGMAR1ALDH1A1MAPTKDM4EPTGS2 | |
| SCHEMBL14689869 | 0.79 | HSD17B1 (0.42) | CYP1A2MAPTGAA | |
| SCHEMBL11133453 | 0.78 | BACE1 (0.41) | SIGMAR1CYP1A2ALDH1A1MAPTKDM4E | |
| SCHEMBL2721721 | 0.75 | BACE1 (0.53) | BRD4ALDH1A1MAPTKDM4ETHRB | |
| SCHEMBL7799451 | 0.72 | SIGMAR1 (0.56) | SIGMAR1HTR2CCYP1A2ALDH1A1MAPT | |
| SCHEMBL24948978 | 0.71 | HSP90AA1 (0.43) | MAPTPTGS2PTGS1HSP90AA1FGFR1 | |
| SCHEMBL29822613 | 0.71 | NOTUM (0.36) | NOTUMCYP1A2ALDH1A1MAPTKDM4E | |
| SCHEMBL13384396 | 0.69 | CYP3A4 (0.41) | SIGMAR1CYP1A2ALDH1A1MAPTPTGS2 | |
| SCHEMBL10761030 | 0.68 | CYP3A4 (0.43) | SIGMAR1HTR2CJAK2NTRK1MET | |
| SCHEMBL30379506 | 0.68 | CYP1A2 (0.36) | SIGMAR1HTR2CCYP1A2MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188088-B2 | Ethenyl carboxamide derivatives useful as microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-29 | — | — | US | disclosed |
| US-8188088-B2 | Ethenyl carboxamide derivatives useful as microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-29 | — | — | US | disclosed |
| US-8188088-B2 | Ethenyl carboxamide derivatives useful as microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-29 | — | — | US | disclosed |
| US-20090318495-A1 | ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-24 | — | — | US | disclosed |
| US-20090318495-A1 | ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-24 | — | — | US | disclosed |
| US-20090318495-A1 | ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-12-24 | — | — | US | disclosed |
| EP-2029530-A1 | ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | Syngeta Participations AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007144174-A1 | ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007144174-A1 | ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318495-A1 | ETHENYL CARBOXAMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | CD14, MSR1, ELANE | SIGMAR1 440/4885HTR2C 1811/4885NOTUM 2254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.