Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539989 | 0.82 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EALOX5SMN1; SMN2 | |
| SCHEMBL3604278 | 0.80 | POLB (0.42) | MEN1KMT2APARP1KDM4EALOX5 | |
| SCHEMBL11348217 | 0.79 | MEN1 (0.39) | TDP1TP53MEN1KMT2AKDM4E | |
| SCHEMBL653135 | 0.77 | S100B (0.50) | TDP1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4919799 | 0.77 | SIGMAR1 (0.42) | TP53MEN1KMT2AKDM4EALOX5 | |
| SCHEMBL15174259 | 0.76 | KDM4E (0.39) | MEN1KMT2AKDM4EALOX5SMN1; SMN2 | |
| SCHEMBL6114258 | 0.76 | HPGD (0.51) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11513064 | 0.75 | LMNA (0.41) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11548076 | 0.75 | SMN1; SMN2 (0.40) | MEN1KMT2AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL2749288 | 0.75 | AKR1C3 (0.36) | TP53MEN1KMT2APARP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611109-A4 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-06-24 | — | — | EP | disclosed |
| EP-1611109-A1 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004087680-A1 | NOVEL QUINAZOLINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2004-10-14 | — | — | WO | disclosed |
| EP-0397511-B1 | Novel cephalosporin compounds and processes for preparation thereof | LUCKY LTD (KR) | 1996-09-04 | — | — | EP | disclosed |
| US-5202315-A | Antiboiotic | LUCKY, LTD. (KR) | 1993-04-13 | — | — | US | disclosed |
| WO-1992008721-A1 | NOVEL CEPHALOSPORIN COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | LUCKY, LTD. (KR) | 1992-05-29 | — | — | WO | disclosed |
| EP-0397511-A2 | Novel cephalosporin compounds and processes for preparation thereof | LUCKY, LTD. (KR) | 1990-11-14 | — | — | EP | disclosed |
| US-4816235-A | Silver and manganese recovery using acidified thiourea | PESIC BATRIC (US) | 1989-03-28 | — | — | US | disclosed |
| US-4778519-A | Recovery of precious metals from a thiourea leach | PESIC BATRIC (US) | 1988-10-18 | — | — | US | disclosed |
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |
| US-3994719-A | Resins for separating heavy metals consisting of thiourea-group-containing macroporous vinyl aromatic crosslinked matrixes | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |