SCHEMBL4199599

SCHEMBL4199599

CC(OOC(C)(C)C)c1ccc(N(C)C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.42
ALDH1A1 P00352 7/20 0.41
TSHR P16473 5/20 0.41
HSD17B10 Q99714 2/20 0.41
ALOX15 P16050 2/20 0.41
GAA P10253 4/20 0.39
ATM Q13315 1/20 0.39
KMT2A Q03164 5/20 0.36
MEN1 O00255 4/20 0.36
CYP3A4 P08684 3/20 0.35
MAPK1 P28482 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CYP1A2 P05177 1/20 0.35
MAPT P10636 1/20 0.35
PHLPP2 Q6ZVD8 1/20 0.35
TP53 P04637 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7654223 0.76 RIPK1 (0.39) ALDH1A1TSHRHSD17B10ATMMAPK1
SCHEMBL4187976 0.74 GAA (0.40) SLC2A1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL11989520 0.70 ALDH1A1 (0.50) SLC2A1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL3893552 0.68 ALDH1A1 (0.61) SLC2A1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL10145543 0.68 ALDH1A1 (0.61) SLC2A1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL346292 0.68 ALDH1A1 (0.61) SLC2A1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL3382197 0.67 SLC2A1 (0.55) SLC2A1ALDH1A1TSHRHSD17B10ALOX15
Ethane SCHEMBL27650935 0.67 ALDH1A1 (0.46) SLC2A1ALDH1A1TSHRHSD17B10ALOX15
SCHEMBL435293 0.67 SLC2A1 (0.42) SLC2A1ALDH1A1TSHRHSD17B10ALOX15
Hydrochloric Acid SCHEMBL2861214 0.66 ALDH1A1 (0.58) SLC2A1ALDH1A1TSHRHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1642934-B1 TRANSPARENT RESIN COMPOSITION SANYO CHEMICAL IND LTD (JP) 2012-12-12 EP disclosed
US-7619037-B2 Transparent resin composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2009-11-17 US disclosed
US-20060281860-A1 Transparent resin composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-12-14 US disclosed
EP-1642934-A1 TRANSPARENT RESIN COMPOSITION SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-04-05 EP disclosed
US-6491903-B1 NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY WASHINGTON UNIVERSITY 2002-12-10 US disclosed
US-6383500-B1 Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications WASHINGTON UNIVERSITY 2002-05-07 US disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed