SCHEMBL4187976

SCHEMBL4187976

CC(COOC(C)(C)C)c1ccc(N(C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.40
SLC2A1 P11166 1/20 0.39
MEN1 O00255 5/20 0.38
KMT2A Q03164 5/20 0.38
ALDH1A1 P00352 6/20 0.37
TSHR P16473 3/20 0.37
HSD17B10 Q99714 2/20 0.37
ALOX15 P16050 1/20 0.37
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL361156 0.88 RIPK1 (0.35) ALDH1A1TSHR
SCHEMBL4084906 0.82 IDO1 (0.37) L3MBTL1HPGDHTT
SCHEMBL1077953 0.79 RIPK1 (0.48) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL19416734 0.77 ALDH1A1 (0.49) GAASLC2A1MEN1KMT2AALDH1A1
SCHEMBL449053 0.76
SCHEMBL28217326 0.75 RIPK1 (0.44)
SCHEMBL16703233 0.74
SCHEMBL449071 0.74 RIPK1 (0.35)
SCHEMBL4199599 0.74 SLC2A1 (0.42) GAASLC2A1MEN1KMT2AALDH1A1
SCHEMBL6166517 0.72 RIPK1 (0.32) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1642934-B1 TRANSPARENT RESIN COMPOSITION SANYO CHEMICAL IND LTD (JP) 2012-12-12 EP disclosed
US-7619037-B2 Transparent resin composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2009-11-17 US disclosed
US-20060281860-A1 Transparent resin composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-12-14 US disclosed
EP-1642934-A1 TRANSPARENT RESIN COMPOSITION SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-04-05 EP disclosed
US-6491903-B1 NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY WASHINGTON UNIVERSITY 2002-12-10 US disclosed
US-6383500-B1 Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications WASHINGTON UNIVERSITY 2002-05-07 US disclosed
EP-0910351-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. Searle & Co. (US) 1999-04-28 EP disclosed
WO-1997049387-A1 PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS G.D. SEARLE AND CO. (US) 1997-12-31 WO disclosed