Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13731468 | 0.89 | MAPT (0.52) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL28958210 | 0.88 | KMT2A (0.50) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL29803178 | 0.87 | CA12 (0.58) | CA12CYP1A2CYP3A4ATMCA9 | |
| Sulfuric Acid SCHEMBL20299328 | 0.83 | CA2 (0.49) | CA12KMT2ACA1CA2ALDH1A1 | |
| N-Benzylmethylamine SCHEMBL20239926 | 0.82 | CYP3A4 (0.59) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL5939339 | 0.81 | FFAR1 (0.56) | ATMKMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28338890 | 0.81 | L3MBTL1 (0.58) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL10706446 | 0.80 | MAOA (0.53) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL10806824 | 0.80 | MAOA (0.53) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL4455333 | 0.79 | CA12 (0.49) | CA12CYP1A2CYP3A4CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119368011-A | Polyamide composite film | 万华化学集团股份有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-222263523-U | Perovskite solar cell | 旗滨新能源发展(深圳)有限责任公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-113825530-A | Dual mode18F-labelled thermal compounds and use thereof | 省卫生服务机构 | 2021-12-21 | — | — | CN | disclosed |
| WO-2021027306-A1 | DIHYDROARTEMISININ-STEROID CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | 云白药征武科技(上海)有限公司 | 2021-02-18 | — | — | WO | disclosed |
| CN-110678174-A | Prodrugs of treprostinil | 联合治疗学有限公司 | 2020-01-10 | — | — | CN | disclosed |
| US-7473669-B2 | Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones, and their use as fungicides | DOW AGROSCIENCES LLC (US) | 2009-01-06 | — | — | US | disclosed |
| EP-1881966-A2 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-6-ONES, 1,2,4-TRIANZIN-6-ONES, AND THEIR USE AS FUNGICIDES | Dow AgroSciences LLC (US) | 2008-01-30 | — | — | EP | disclosed |
| WO-2006119400-A2 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-6-ONES, 1,2,4-TRIANZIN-6-ONES, AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20060252755-A1 | Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones, and their use as fungicides | DOW AGROSCIENCES LLC | 2006-11-09 | — | — | US | disclosed |
| CN-1213144-C | Recombination nucleic acid molecule and application thereof | REGENT OF UNIV OF CALIFORNIA (US) | 2005-08-03 | — | — | CN | disclosed |
| CN-1066731-C | Substrates for beta-lactamases and uses thereof | UNIV CALIFORNIA (US) | 2001-06-06 | — | — | CN | disclosed |
| CN-1296078-A | Recombination nucleic acid molecule and application thereof | REGENT OF UNIV OF CALIFORNIA (US) | 2001-05-23 | — | — | CN | disclosed |
| CN-1184479-A | Substrates for beta-lactamases and uses thereof | UNIV CALIFORNIA (US) | 1998-06-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252755-A1 | Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones, and their use as fungicides | DDT, CYP4B1, CYP4X1 | CA12 3570/4885CYP1A2 9/4885CYP3A4 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.