Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5120809 | 0.74 | ADRA2A (0.47) | ABHD6HTTKMT2A | |
| SCHEMBL9403398 | 0.74 | PRNP (0.46) | ABHD6HTTKMT2A | |
| SCHEMBL30471092 | 0.69 | ABHD6 (0.35) | ABHD6HTTKMT2A | |
| SCHEMBL3020052 | 0.68 | PNMT (0.46) | ABHD6 | |
| SCHEMBL2303460 | 0.68 | ASIC3 (0.46) | ABHD6 | |
| SCHEMBL31394726 | 0.68 | DYRK1A (0.32) | ABHD6HTTKMT2A | |
| SCHEMBL29762650 | 0.68 | PNMT (0.50) | — | |
| SCHEMBL21591692 | 0.68 | PNMT (0.50) | — | |
| SCHEMBL15309401 | 0.64 | TNKS2 (0.41) | ABHD6HTTKMT2A | |
| SCHEMBL29727983 | 0.64 | PNMT (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062291-A1 | PHOSPHODIESTERASE 10 INHIBITORS | AMGEN INC. | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062291-A1 | PHOSPHODIESTERASE 10 INHIBITORS | PDE10A, PDE12, PDE5A | ABHD6 874/4885HTT 3186/4885KMT2A 2494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.