Thymine

Thymine

SCHEMBL4201976

Cc1c[nH]c(=O)[nH]c1=O.OC[C@H]1OC[C@H](O)[C@@H]1O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.50
GAA P10253 2/20 0.33
MAPT P10636 1/20 0.33
TK1 P04183 2/20 0.32
ALDH1A1 P00352 1/20 0.32
ALB P02768 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
5-Bromouracil SCHEMBL4201154 0.85 PYGM (0.39) ATAD2GAAMAPTTK1ALDH1A1
SCHEMBL4284709 0.84 DPYD (0.50) GAAMAPTTK1
Fluorouracil SCHEMBL4289411 0.84 LMNA (0.50) GAAMAPTTK1ALDH1A1
Ribose (Furanose) SCHEMBL1851842 0.80 ATAD2 (0.54) ATAD2ALDH1A1
Ribose (Furanose) SCHEMBL5521544 0.80 ATAD2 (0.54) ATAD2ALDH1A1
D-Galactose SCHEMBL16581344 0.78 ATAD2 (0.53) ATAD2ALDH1A1
Dextrose SCHEMBL6692229 0.78 ATAD2 (0.53) ATAD2ALDH1A1
SCHEMBL4205792 0.77 MPO (0.32) TK1
Uracil SCHEMBL4193859 0.76 CRBN (0.47) GAAALDH1A1
SCHEMBL4190649 0.75 MMP2 (0.49) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397706-A Serum-free basal and culture medium for hematopoietic and leukemia cells CORREA PAULO N (CA) 1995-03-14 US claimed
WO-1993009220-A1 CELL CULTURE MEDIUM CORREA PAULO N (CA) 1993-05-13 WO claimed
EP-0122151-B1 PRODUCTION OF PRIMARY OR SECONDARY ALCOHOL DERIVATIVES OF PHOSPHOLIPIDS BY THE ENZYMATIC TECHNIQUE MEITO SANGYO KABUSHIKI KAISHA (JP) 1989-02-15 EP claimed
US-4783402-A Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1988-11-08 US claimed
EP-3533863-B1 PROCESS FOR REDUCING UNWANTED CULTURE BYPRODUCTS IN CELL CULTURE MEDIUM SAMSUNG BIOEPIS CO LTD (KR) 2026-03-25 EP disclosed
US-20230203554-A1 PROCESS FOR REDUCING UNWANTED CULTURE BYPRODUCTS IN CELL CULTURE MEDIUM SAMSUNG BIOEPIS CO LTD (KR) 2023-06-29 US disclosed
EP-3533863-A1 PROCESS FOR REDUCING UNWANTED CULTURE BYPRODUCTS IN CELL CULTURE MEDIUM Samsung Bioepis Co., Ltd. (KR) 2019-09-04 EP disclosed
US-8754058-B2 Inhibitors of FAM3B gene, inhibitor compositions, inhibiting methods and applications of inhibitors in preparing pharmaceuticals Suzhou Ribo Life Science Company, Ltd. (CN) 2014-06-17 US disclosed
US-20130046006-A1 INHIBITORS OF FAM3B GENE, INHIBITOR COMPOSITIONS, INHIBITING METHODS AND APPLICATIONS OF INHIBITORS IN PREPARING PHARMACEUTICALS Suzhou Ribo Life Science Co., Ltd. (CN) 2013-02-21 US disclosed
CN-102471300-A Compositions and methods for enhancing viral potency OTTAWA HOSPITAL RES INST 2012-05-23 CN disclosed
US-7608402-B2 DNA methylation specific signal amplification LI WEIWEI 2009-10-27 US disclosed
US-20090181373-A1 DNA methylation specific signal amplification LI WEIWEI 2009-07-16 US disclosed
US-5397706-A Serum-free basal and culture medium for hematopoietic and leukemia cells CORREA PAULO N (CA) 1995-03-14 US disclosed
WO-1993009220-A1 CELL CULTURE MEDIUM CORREA PAULO N (CA) 1993-05-13 WO disclosed
EP-0122151-B1 PRODUCTION OF PRIMARY OR SECONDARY ALCOHOL DERIVATIVES OF PHOSPHOLIPIDS BY THE ENZYMATIC TECHNIQUE MEITO SANGYO KABUSHIKI KAISHA (JP) 1989-02-15 EP disclosed
US-4783402-A Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1988-11-08 US disclosed
CN-85107547-A Microchemiluminescent detection system 1987-04-15 CN disclosed
EP-0122151-A2 Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique MEITO SANGYO KABUSHIKI KAISHA (JP) 1984-10-17 EP disclosed
US-4404368-A Lyophilized phosphorylated nucleosides ENS BIOLOGICALS INC. (CA) 1983-09-13 US disclosed
EP-0058563-A1 Lyophilized phosphorylated nucleosides ens BIO LOGICALS INC. (CA) 1982-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130046006-A1 INHIBITORS OF FAM3B GENE, INHIBITOR COMPOSITIONS, INHIBITING METHODS AND APPLICATIONS OF INHIBITORS IN PREPARING PHARMACEUTICALS FAM222B, FAM162A, FAM20C ATAD2 865/4885GAA 304/4885MAPT 3896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.