Phencyclidine

Phencyclidine

SCHEMBL5166553

[Ag].c1ccc(C2(N3CCCCC3)CCCCC2)cc1

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.96
GRIN1 Q05586 5/20 0.96
GRIN2A Q12879 5/20 0.96
GRIN2B Q13224 5/20 0.96
PRCP P42785 3/20 0.96
GRIN2D O15399 1/20 0.96
GRIN3B O60391 1/20 0.96
CYP2B6 P20813 1/20 0.96
SLC6A2 P23975 1/20 0.96
SLC6A4 P31645 1/20 0.96
SLC6A3 Q01959 1/20 0.96
KCNH2 Q12809 1/20 0.96
GRIN2C Q14957 1/20 0.96
GRIN3A Q8TCU5 1/20 0.96
OPRM1 P35372 3/20 0.92
OPRD1 P41143 1/20 0.92
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
TP53 P04637 1/20 0.53
CYP1A2 P05177 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phencyclidine SCHEMBL42022 0.98 SIGMAR1 (1.00) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Phencyclidine SCHEMBL17008793 0.98 SIGMAR1 (1.00) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
SCHEMBL9153279 0.98 SIGMAR1 (1.00) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Rolicyclidine SCHEMBL517928 0.98 SIGMAR1 (1.00) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Phencyclidine SCHEMBL21777 0.96 OPRM1 (1.00) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Phencyclidine SCHEMBL9431514 0.94 SIGMAR1 (0.92) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
SCHEMBL3407261 0.94 GRIN1 (0.92) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
SCHEMBL28282384 0.92 GRIN1 (0.88) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Phencyclidine SCHEMBL28296317 0.91 GRIN1 (0.86) SIGMAR1GRIN1GRIN2AGRIN2BPRCP
Phencyclidine SCHEMBL28239746 0.91 GRIN1 (0.86) SIGMAR1GRIN1GRIN2AGRIN2BPRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070141541-A1 ASSESSMENT IN COGNITIVE TRAINING EXERCISES POSIT SCIENCE CORPORATION (US) 2007-06-21 US disclosed
US-20070134631-A1 Progressions in HiFi assessments POSIT SCIENCE CORPORATION (US) 2007-06-14 US disclosed
EP-1774490-A1 A METHOD FOR ENHANCING MEMORY AND COGNITION IN AGING ADULTS Neuroscience Solutions Corporation (US) 2007-04-18 EP disclosed
WO-2006019393-A2 A METHOD FOR ENHANCING MEMORY AND COGNITION IN AGING ADULTS NEUROSCIENCE SOLUTIONS CORPORATION (US) 2006-02-23 WO disclosed