SCHEMBL420308

SCHEMBL420308

O=C(O)c1ccc(Oc2ccc(Sc3ccc(Oc4cccc(C(=O)O)c4C(=O)O)cc3)cc2)cc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.50
HPSE Q9Y251 1/20 0.47
PYGL P06737 10/20 0.46
PYGM P11217 11/20 0.43
TDP1 Q9NUW8 3/20 0.43
GALK1 P51570 1/20 0.43
CASP6 P55212 1/20 0.43
MCL1 Q07820 1/20 0.43
PLEC Q15149 1/20 0.43
KDM4E B2RXH2 1/20 0.43
DUSP3 P51452 1/20 0.42
PTPN5 P54829 1/20 0.42
PTPN11 Q06124 1/20 0.42
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.39
MITF O75030 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL422032 0.92 POLB (0.57) POLBHPSEPYGLPYGMTDP1
SCHEMBL425870 0.91 CTNNB1 (0.42) POLBHPSETDP1KDM4ELMNA
SCHEMBL5086008 0.89 POLB (0.48) POLBHPSEPYGLPYGMTDP1
SCHEMBL29404149 0.89 PYGL (0.53) POLBHPSEPYGLPYGMTDP1
SCHEMBL716921 0.89 PYGL (0.53) POLBHPSEPYGLPYGMTDP1
SCHEMBL3417323 0.88 TDP1 (0.54) POLBHPSEPYGLPYGMTDP1
SCHEMBL425842 0.86 POLB (0.70) POLBHPSEPYGLPYGMTDP1
SCHEMBL29373765 0.85 POLB (0.61) POLBHPSEPYGLPYGMTDP1
SCHEMBL126199 0.85 POLB (0.61) POLBHPSEPYGLPYGMTDP1
SCHEMBL421351 0.84 POLB (0.59) POLBHPSEPYGLPYGMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11905381-B2 Polyimide microparticles XEROX CORPORATION (US) 2024-02-20 US claimed
EP-4089136-A1 POLYIMIDE MICROPARTICLES Xerox Corporation (US) 2022-11-16 EP claimed
CN-115322398-A Polyimide fine particles 施乐公司 2022-11-11 CN claimed
US-9161440-B2 Articles comprising a polyimide solvent cast film having a low coefficient of thermal expansion and method of manufacture thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-10-13 US claimed
EP-2032634-B1 POLYIMIDE SOLVENT CAST FILMS HAVING LOW COEFFICIENT OF THERMAL EXPANSION AND METHOD OF MANUFACTURE THEREOF GEN ELECTRIC (US) 2015-05-13 EP claimed
EP-2041209-B1 ARTICLES COMPRISING A POLYIMIDE SOLVENT CAST FILM HAVING A LOW COEFFICIENT OF THERMAL EXPANSION AND METHOD OF MANUFACTURE THEREOF SABIC INNOVATIVE PLASTICS IP (NL) 2014-11-26 EP claimed
EP-2081977-B1 ARTICLES COMPRISING A POLYIMIDE SOLVENT CAST FILM HAVING A LOW COEFFICIENT OF THERMAL EXPANSION AND METHOD OF MANUFACTURE THEREOF SABIC INNOVATIVE PLASTICS IP (NL) 2013-12-11 EP claimed
US-8568867-B2 Polyimide solvent cast films having a low coefficient of thermal expansion and method of manufacture thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-10-29 US claimed
US-8545975-B2 Articles comprising a polyimide solvent cast film having a low coefficient of thermal expansion and method of manufacture thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-10-01 US claimed
US-8545988-B2 Polyetherimide and polyetherimide sulfone blends having automotive lighting applications SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-10-01 US claimed
US-20030225221-A1 High performance thermoplastic compositions with improved melt flow properties SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2003-12-04 US claimed
US-20030216506-A1 Method of manufacture of polyester molding compositions and articles produced therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2003-11-20 US claimed
WO-2003080709-A1 PREPARATION OF POLYIMIDE POLYMERS GENERAL ELECTRIC COMPANY (US) 2003-10-02 WO claimed
US-20030181626-A1 Preparation of polyimide polymers SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2003-09-25 US claimed
US-20030125478-A1 HIGH PERFORMANCE THERMOPLASTIC COMPOSITIONS WITH IMPROVED MELT FLOW PROPERTIES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2003-07-03 US claimed
EP-1318174-A1 Method of manufacture of polyester molding compositions and articles produced therefrom GENERAL ELECTRIC COMPANY (US) 2003-06-11 EP claimed
WO-2003040213-A1 HIGH MOLECULAR WEIGHT POLY(IMIDE)S AND METHODS OF SYNTHESIS THEREOF GENERAL ELECTRIC COMPANY (US) 2003-05-15 WO claimed
EP-1287076-A2 HIGH PERFORMANCE THERMOPLASTIC COMPOSITIONS WITH IMPROVED MELT FLOW PROPERTIES GENERAL ELECTRIC COMPANY (US) 2003-03-05 EP claimed
US-6500904-B1 FROM THE COUPLING OF LOWER MOLECULAR WEIGHT FUNCTIONALIZED PRECURSOR POLYIMIDES GENERAL ELECTRIC COMPANY 2002-12-31 US claimed
WO-2001096477-A2 HIGH PERFORMANCE THERMOPLASTIC COMPOSITIONS WITH IMPROVED MELT FLOW PROPERTIES GENERAL ELECTRIC COMPANY (US) 2001-12-20 WO claimed