Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206391 | 0.80 | CLK1 (0.37) | — | |
| SCHEMBL4243866 | 0.76 | ALDH1A1 (0.34) | ALDH1A1GFERPOLBTDP1 | |
| SCHEMBL8059196 | 0.74 | TXNRD1 (0.34) | TXNRD1 | |
| SCHEMBL1848182 | 0.73 | POLB (0.46) | ALDH1A1GFERPDE10APOLBTDP1 | |
| SCHEMBL14032510 | 0.73 | NNMT (0.44) | ALDH1A1GFERPDE10APOLBTDP1 | |
| SCHEMBL25179865 | 0.73 | ALDH1A1 (0.47) | ALDH1A1GFERTXNRD1PDE10APOLB | |
| SCHEMBL15668836 | 0.72 | ALDH1A1 (0.35) | ALDH1A1GFERTXNRD1PDE10A | |
| SCHEMBL4009723 | 0.69 | ALDH1A1 (0.34) | ALDH1A1GFERPDE10APOLBTDP1 | |
| SCHEMBL4215098 | 0.67 | ABCB11 (0.38) | ALDH1A1TXNRD1PDE10APOLBTDP1 | |
| SCHEMBL19126900 | 0.66 | POLB (0.34) | TXNRD1PDE10APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312306-A1 | TETRAHYDRO-5H-PYRIDO[2,3-D]AZEPINES AS 5-HT2C LIGANDS | CASCADE THERAPEUTICS INC. (CA) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312306-A1 | TETRAHYDRO-5H-PYRIDO[2,3-D]AZEPINES AS 5-HT2C LIGANDS | HTR2C, HTR2A, HTR5A | ALDH1A1 1316/4885GFER 4212/4885TXNRD1 1578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.