Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.68 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.68 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264048 | 1.00 | PRSS1 (0.68) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL3745080 | 0.98 | PRSS1 (0.66) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| Benzoic Acid SCHEMBL8017354 | 0.96 | PRSS1 (0.63) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL633459 | 0.95 | PRSS1 (0.62) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL571011 | 0.95 | PRSS1 (0.65) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL3320267 | 0.94 | PRSS1 (0.77) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL27678787 | 0.93 | PRSS1 (0.59) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL30437742 | 0.93 | PRSS1 (0.74) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL2822334 | 0.92 | PRSS1 (0.64) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| Benzoic Acid SCHEMBL28210602 | 0.92 | PRSS1 (0.58) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 513 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115175665-B | Drug containing Sofospiramide | 科研制药株式会社 | 2024-04-16 | — | — | CN | claimed |
| US-20240041748-A1 | INVERSE EMULSION COMPRISING AT LEAST ONE FATTY ALCOHOL, A NON-IONIC SUGAR ESTER, ETHYLCELLULOSE AND METHOD EMPLOYING IT | L'OREAL (FR) | 2024-02-08 | — | — | US | claimed |
| CN-117042748-A | Inverse emulsion comprising at least one fatty alcohol, a nonionic sugar ester, ethylcellulose, and a method employing the inverse emulsion | 莱雅公司 | 2023-11-10 | — | — | CN | claimed |
| EP-4262684-A1 | INVERSE EMULSION COMPRISING AT LEAST ONE FATTY ALCOHOL, A NON-IONIC SUGAR ESTER, ETHYLCELLULOSE AND METHOD EMPLOYING IT | L'OREAL (FR) | 2023-10-25 | — | — | EP | claimed |
| US-20230241044-A1 | TREATMENT FOR PSORIASIS AND SKIN INFLAMMATORY DISEASES | ZYDUS LIFESCIENCES LIMITED (IN) | 2023-08-03 | — | — | US | claimed |
| US-20230149349-A1 | MEDICAMENT CONTAINING SOFPIRONIUM BROMIDE | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2023-05-18 | — | — | US | claimed |
| EP-4157233-A1 | TREATMENT FOR PSORIASIS AND SKIN INFLAMMATORY DISEASES | Zydus Lifesciences Limited (IN) | 2023-04-05 | — | — | EP | claimed |
| CN-115666539-A | Treatment of psoriasis and skin inflammatory diseases | 兹杜斯生命科学有限公司 | 2023-01-31 | — | — | CN | claimed |
| WO-2022238745-A1 | TOPICAL PHARMACEUTICAL COMPOSITION OF HIF PROLYL HYDROXYLASE INHIBITORS | ZYDUS LIFESCIENCES LIMITED (IN) | 2022-11-17 | — | — | WO | claimed |
| CN-115175665-A | Medicine containing suopyram bromide | 科研制药株式会社 | 2022-10-11 | — | — | CN | claimed |
| WO-2009035484-A1 | LIP GLOSS | NGUYEN LETHU T (US) | 2009-03-19 | — | — | WO | claimed |
| US-20090060857-A1 | LIP GLOSS | COTY S.A.S. (FR) | 2009-03-05 | — | — | US | claimed |
| US-20090047229-A1 | LIP GLOSS | COTY S.A.S (FR) | 2009-02-19 | — | — | US | claimed |
| WO-2008156723-A2 | LIP GLOSS | COTY S.A.S (FR) | 2008-12-24 | — | — | WO | claimed |
| US-20080267896-A1 | Continuous liquid fatty phase; non-silicone oils; for application to skin, hair | L'OREAL S.A. (FR) | 2008-10-30 | — | — | US | claimed |
| US-6579907-B1 | Gelling agent is crosslinked acrylic polymer | L'OREAL S.A. (FR) | 2003-06-17 | — | — | US | claimed |
| US-6344205-B1 | ISONONYL, ISONONANOATE, SILICONE OIL, PULVERULENT COMPOUND | L'OREAL S.A. (FR) | 2002-02-05 | — | — | US | claimed |
| US-20020012643-A1 | MAKE-UP REMOVING COMPOSITION | L'OREAL, S.A. (FR) | 2002-01-31 | — | — | US | claimed |
| US-6162834-A | Foaming oil-in-water emulsion based on nonionic surfactants, a fatty phase and a crosslinked cationic or anionic polymer, and its use in topical applications | L'OREAL (FR) | 2000-12-19 | — | — | US | claimed |
| EP-0739619-B1 | Foaming o/w emulsion based on non-ionic surfactants, a fatty phase and a cross-linked cationic or anionic polymer for topical use | OREAL (FR) | 1998-01-14 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149349-A1 | MEDICAMENT CONTAINING SOFPIRONIUM BROMIDE | SIGMAR1, PEF1, OPRK1 | PRSS1 692/4885PRSS2 772/4885PRSS3 270/4885 |
| US-20080267896-A1 | Continuous liquid fatty phase; non-silicone oils; for application to skin, hair | KRT18, CUTA, DEGS1 | PRSS1 3319/4885PRSS2 2727/4885PRSS3 2780/4885 |
| US-20230241044-A1 | TREATMENT FOR PSORIASIS AND SKIN INFLAMMATORY DISEASES | P4HA1, PAH, TNF | PRSS1 670/4885PRSS2 2541/4885PRSS3 2159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.