Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.53 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501899 | 0.79 | ALOX15 (1.00) | ALDH1A1ALOX15TP53LMNAPOLB | |
| SCHEMBL4209570 | 0.77 | NPSR1 (0.69) | ALDH1A1ALOX15TP53LMNAPOLB | |
| SCHEMBL946948 | 0.76 | HTT (0.75) | ALDH1A1ALOX15TP53LMNAPOLB | |
| Hydrochloric Acid SCHEMBL946927 | 0.74 | HTT (0.72) | ALDH1A1ALOX15TP53LMNAPOLB | |
| SCHEMBL25195278 | 0.74 | ALDH1A1 (0.58) | ALDH1A1ALOX15TP53LMNAPOLB | |
| SCHEMBL25203125 | 0.73 | KCNN2 (0.72) | ALDH1A1ALOX15TP53LMNAPOLB | |
| SCHEMBL11186961 | 0.73 | HTT (0.66) | ALDH1A1ALOX15TP53LMNAPOLB | |
| SCHEMBL11981653 | 0.73 | ALDH1A1 (0.56) | ALDH1A1GLAPOLBMAPK1MAPT | |
| SCHEMBL4219187 | 0.72 | TP53 (0.79) | ALDH1A1ALOX15TP53LMNAPOLB | |
| SCHEMBL4215477 | 0.72 | TP53 (1.00) | ALDH1A1ALOX15TP53LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036475-A1 | Pyrazolyl-Pyrimidines as Potassium Channel Modulating Agents and Their Medical Use | NEUROSEARCH A/S (DK) | 2009-02-05 | — | — | US | disclosed |
| EP-1863796-A1 | PYRAZOLYL-PYRIMIDINES AS POTASSIUM CHANNEL MODULATING AGENTS AND THEIR MEDICAL USE | NeuroSearch A/S (DK) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006100212-A1 | PYRAZOLYL-PYRIMIDINES AS POTASSIUM CHANNEL MODULATING AGENTS AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036475-A1 | Pyrazolyl-Pyrimidines as Potassium Channel Modulating Agents and Their Medical Use | KCND2, KCNJ2, KCNN3 | ALDH1A1 3477/4885ALOX15 4049/4885TP53 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.