Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | KCNN3 | Q9UGI6 | 3/20 | 0.61 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946948 | 0.83 | HTT (0.75) | ALOX15TP53ALDH1A1POLBKCNN3 | |
| Hydrochloric Acid SCHEMBL946927 | 0.81 | HTT (0.72) | ALOX15TP53ALDH1A1POLBKCNN3 | |
| SCHEMBL4215477 | 0.80 | TP53 (1.00) | ALOX15TP53ALDH1A1POLBKCNN3 | |
| SCHEMBL4219187 | 0.80 | TP53 (0.79) | ALOX15TP53ALDH1A1POLBKCNN3 | |
| SCHEMBL4138642 | 0.79 | HTT (0.68) | ALOX15TP53ALDH1A1POLBHTT | |
| SCHEMBL4210136 | 0.79 | ALDH1A1 (1.00) | ALOX15TP53ALDH1A1POLBKCNN3 | |
| SCHEMBL25199209 | 0.77 | TP53 (0.80) | ALOX15TP53ALDH1A1POLBKCNN3 | |
| SCHEMBL4207857 | 0.77 | KCNN3 (0.97) | ALOX15TP53ALDH1A1POLBKCNN3 | |
| SCHEMBL4212917 | 0.77 | TP53 (0.80) | ALOX15TP53POLBKCNN3KCNN2 | |
| SCHEMBL15573820 | 0.77 | POLB (0.72) | ALOX15TP53ALDH1A1POLBKCNN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863796-A1 | PYRAZOLYL-PYRIMIDINES AS POTASSIUM CHANNEL MODULATING AGENTS AND THEIR MEDICAL USE | NeuroSearch A/S (DK) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006100212-A1 | PYRAZOLYL-PYRIMIDINES AS POTASSIUM CHANNEL MODULATING AGENTS AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2006-09-28 | — | — | WO | disclosed |