Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | MDH2 | P40926 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6102227 | 0.85 | KDM4E (0.49) | ALDH1A1MAPTEGFRMEN1KMT2A | |
| SCHEMBL6102218 | 0.82 | MAPT (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8575856 | 0.81 | AKR1C2 (0.53) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL11328482 | 0.75 | KIF11 (0.49) | KIF11ALDH1A1EGFRMEN1KMT2A | |
| SCHEMBL6423153 | 0.74 | CTSV (0.47) | ALDH1A1MAPTHSD17B10LMNA | |
| SCHEMBL6425667 | 0.74 | MTNR1A (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL13802177 | 0.70 | ALDH1A1 (0.46) | KIF11PTGS1PTGS2ALDH1A1MAPT | |
| SCHEMBL4204905 | 0.70 | KDM4E (0.69) | KIF11PTGS1PTGS2ALDH1A1MAPT | |
| SCHEMBL6425282 | 0.69 | MRGPRX4 (0.37) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29152994 | 0.69 | EPHX1 (0.52) | PTGS1PTGS2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| WO-2005092062-A2 | COMPOUNDS FOR NEURODEGENERATIVE DISORDERS | MYRIAD GENETICS, INC. (US) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | KIF11 1937/4885PTGS1 2198/4885PTGS2 2066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.