Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6102227 | 0.85 | KDM4E (0.49) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6102218 | 0.82 | MAPT (0.49) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8578425 | 0.82 | AKR1C2 (0.54) | AKR1C2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4211050 | 0.81 | KIF11 (0.47) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6425667 | 0.81 | MTNR1A (0.47) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL6423153 | 0.81 | CTSV (0.47) | ALDH1A1HSD17B10MAPTPPARGPPARA | |
| SCHEMBL5270294 | 0.79 | AKR1C2 (0.58) | AKR1C2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8891258 | 0.78 | AKR1C2 (0.45) | AKR1C2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11615249 | 0.77 | AKR1C2 (0.48) | AKR1C2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6425282 | 0.76 | MRGPRX4 (0.37) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721347-A | Esters and amides of substituted pyrrole acetic acids | CELL PATHWAYS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0485157-A2 | Esters and amides of substituted pyrrole acetic acids | FGN, INC. (US) | 1992-05-13 | — | — | EP | disclosed |