SCHEMBL4211136

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4221179	0.85	POLB (0.46)	AKR1C3AKR1C2GAAPOLBTAS2R14
	SCHEMBL4219603	0.83	MEN1 (0.51)	AKR1C3AKR1C2FABP4GRIK1KMT2A
	SCHEMBL2276347	0.82	MEN1 (0.56)	GAAPOLBTAS2R14GRIK1KMT2A
	SCHEMBL4226633	0.82	CLCN2 (0.52)	AKR1C3AKR1C2GAAKMT2AMEN1
	SCHEMBL4212766	0.81	AKR1C3 (0.48)	AKR1C3AKR1C2GAATAS2R14KMT2A
	SCHEMBL4215640	0.81	MEN1 (0.52)	AKR1C3AKR1C2FABP4GRIK1KMT2A
	SCHEMBL4220677	0.81	MEN1 (0.56)	AKR1C3AKR1C2TAS2R14GRIK1KMT2A
	SCHEMBL1358523	0.80	TAS2R14 (0.75)	AKR1C3AKR1C2TAS2R14FABP4GRIK1
	SCHEMBL4221452	0.80	TDP1 (0.51)	AKR1C3AKR1C2GAAFABP4KMT2A
	SCHEMBL4217206	0.80	MEN1 (0.61)	AKR1C3AKR1C2FABP4GRIK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.