Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 6/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899939 | 0.83 | PGR (0.42) | MAOBPGR | |
| SCHEMBL4215079 | 0.82 | MAOB (0.43) | MAOBGAAALDH1A1 | |
| SCHEMBL4211464 | 0.78 | PDE3B (0.51) | PDE3BPDE3AGAAALDH1A1 | |
| SCHEMBL22309145 | 0.75 | PDE3B (0.42) | PDE3BPDE3APGR | |
| SCHEMBL4361638 | 0.74 | AXL (0.52) | PDE3BPDE3AMAOBGAAALDH1A1 | |
| SCHEMBL7355155 | 0.74 | KCNH2 (0.44) | PDE3BPDE3AGAAAXL | |
| SCHEMBL22308341 | 0.73 | MAPT (0.39) | PDE3BPDE3AMAOBGAAAXL | |
| SCHEMBL7284129 | 0.71 | CYP3A4 (0.39) | PDE3BPDE3AALDH1A1AXL | |
| SCHEMBL12847195 | 0.70 | AXL (0.56) | PDE3BPDE3AMAOBGAAALDH1A1 | |
| SCHEMBL22309155 | 0.69 | PDE3B (0.47) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7494996-B2 | Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones and their use as fungicides and insecticides | DOW AGROSCIENCES LLC (US) | 2009-02-24 | — | — | US | disclosed |
| EP-1337150-A4 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-6-ONES, 1,2,4-TRIAZIN-6-ONES, AND THEIR USE AS FUNGICIDES AND INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2007-09-26 | — | — | EP | disclosed |
| US-20040242580-A1 | Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones and their use as fungicides and insecticides | KELLY MARTHA JEAN (US) | 2004-12-02 | — | — | US | disclosed |
| EP-1337150-A2 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-6-ONES, 1,2,4-TRIAZIN-6-ONES, AND THEIR USE AS FUNGICIDES AND INSECTICIDES | Dow AgroSciences LLC (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002067675-A2 | SUBSTITUTED 4,5-DIHYDRO-1,2,4-TRIAZIN-6-ONES, 1,2,4-TRIAZIN-6-ONES, AND THEIR USE AS FUNGICIDES AND INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2002-09-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242580-A1 | Substituted 4,5-dihydro-1,2,4-triazin-6-ones, 1,2,4-triazin-6-ones and their use as fungicides and insecticides | DDT, CYP4B1, CYP4X1 | PDE3B 997/4885PDE3A 815/4885MAOB 1482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.