Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 6/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13550115 | 0.86 | GABRB3 (0.42) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL30849289 | 0.86 | RXRA (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL31513958 | 0.86 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL5355959 | 0.80 | ALDH1A1 (0.32) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL22366835 | 0.80 | TDP1 (0.38) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL22366922 | 0.80 | GABRB3 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL27853403 | 0.78 | CES2 (0.38) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL981089 | 0.78 | ALDH1A1 (0.46) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL29129632 | 0.77 | PDE2A (0.32) | PDE2A | |
| SCHEMBL10680627 | 0.77 | GABRB3 (0.36) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621270-B | Condensed ring aromatic compound and application thereof in electroluminescent device | 清华大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-114621269-B | Condensed ring aromatic compound and application thereof in electroluminescent device | 清华大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-114621270-A | Fused aromatic compound and application thereof in electroluminescent device | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-114621269-A | Fused aromatic compound and application thereof in electroluminescent device | 清华大学 | 2022-06-14 | — | — | CN | disclosed |
| EP-2310357-B1 | POTASSIUM ION CHANNEL MODULATORS & USES THEREOF | RAMOT AT TEL AVIV UNIV LIMITED (IL) | 2019-09-11 | — | — | EP | disclosed |
| EP-3412658-A1 | PROCESSES FOR THE MANUFACTURE OF SULFUR-SUBSTITUED PYRAZOLE DERIVATIVES | SOLVAY SA (BE) | 2018-12-12 | — | — | EP | disclosed |
| US-9675567-B2 | Potassium ion channel modulators and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-06-13 | — | — | US | disclosed |
| US-20160374969-A1 | POTASSIUM ION CHANNEL MODULATORS & USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-12-29 | — | — | US | disclosed |
| US-9464052-B2 | Potassium ion channel modulators and uses thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-10-11 | — | — | US | disclosed |
| EP-2470498-B1 | CARBOCYCLIC GLYT1 RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2015-02-11 | — | — | EP | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5739083-A | LOW IN TOXICITY AND PERSISTENCE | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0802191-A1 | PYRAZOLE DERIVATIVES AND INSECTICIDAL COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-10-22 | — | — | EP | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| US-5380865-A | Halogen substituents | MAY & BAKER LIMITED (GB) | 1995-01-10 | — | — | US | disclosed |
| US-5206257-A | Controlling plant nematodes, helminth, protozoa | MAY & BAKER LIMITED (GB) | 1993-04-27 | — | — | US | disclosed |
| EP-0283173-A1 | Pesticidal method using 2-phenylimidazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-09-21 | — | — | EP | disclosed |
| US-4584396-A | Substituted phenoxypropionates and herbicidal compositions | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-04-22 | — | — | US | disclosed |
| US-4441913-A | PRE- AND POST-EMERGENCE | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160374969-A1 | POTASSIUM ION CHANNEL MODULATORS & USES THEREOF | KCNJ11, KCNJ1, KCNJ2 | GABRB3 316/4885GABRA2 274/4885GABRB2 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.