Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL4218342

O=C(O)C(F)(F)F.O=C(O)c1ccc(CCc2ccccc2)cc1Nc1cncc2ccccc12

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CDC25B P30305 2/20 0.42
▸ KDM4C Q9H3R0 8/20 0.41
▸ KDM6B O15054 6/20 0.41
▸ HDAC6 Q9UBN7 1/20 0.40
▸ KDM4D Q6B0I6 3/20 0.40
▸ EGLN3 Q9H6Z9 1/20 0.40
▸ TAS2R14 Q9NYV8 1/20 0.39
▸ TRPV1 Q8NER1 5/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ ADRA2A P08913 1/20 0.38
▸ ADRA2B P18089 1/20 0.38
▸ ADRA2C P18825 1/20 0.38
▸ ADRA1A P35348 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ KDM4A O75164 1/20 0.38
▸ KDM5A P29375 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13890914 0.94 KDM4C (0.46) CDC25BKDM4CKDM6BHDAC6KDM4D
Trifluoroacetic Acid SCHEMBL4218730 0.89 TRPV1 (0.51) KDM4CKDM6BTRPV1KDM4E
SCHEMBL4218343 0.86 HDAC6 (0.38) CDC25BKDM4CHDAC6TRPV1ADRA2A
Trifluoroacetic Acid SCHEMBL4222841 0.84 ACLY (0.45) CDC25BKDM4CTAS2R14ADRA2AADRA2B
SCHEMBL4210974 0.82 TRPV1 (0.56) KDM4CKDM6BKDM4DEGLN3TRPV1
SCHEMBL4211104 0.82 HDAC6 (0.39) CDC25BHDAC6TRPV1ADRA2AADRA2B
Trifluoroacetic Acid SCHEMBL4220424 0.78 TRPV1 (0.45) HDAC6TAS2R14TRPV1MEN1RECQL
SCHEMBL4209243 0.76 ACLY (0.49) CDC25BKDM4CADRA2AADRA2BADRA2C
SCHEMBL4218736 0.76 TRPV1 (0.48) TRPV1KDM4E
SCHEMBL4211136 0.74 AKR1C3 (0.54) TAS2R14MEN1RECQLBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8327467-B2 Anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2012-12-11 — — US disclosed
EP-1860098-B1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO LTD (JP) 2012-11-14 — — EP disclosed
US-20090105474-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-04-23 — — US disclosed
EP-1860098-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-11-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105474-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP11, MMP3 CDC25B 3872/4885KDM4C 1892/4885KDM6B 2594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback