Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4222020 | 0.92 | AQP1 (0.39) | AQP1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL4226280 | 0.92 | MCOLN3 (0.36) | AQP1BRD4MAPTKMT2AMEN1 | |
| SCHEMBL4225686 | 0.91 | AQP1 (0.39) | AQP1MAPTKMT2AALDH1A1GAA | |
| SCHEMBL4226492 | 0.90 | ALDH1A1 (0.36) | AQP1BRD4MAPTALDH1A1CYP3A4 | |
| SCHEMBL4235761 | 0.89 | AQP1 (0.50) | AQP1MAPTKMT2AALDH1A1CYP3A4 | |
| SCHEMBL4221920 | 0.87 | ALDH1A1 (0.35) | AQP1MAPTKMT2AALDH1A1CYP3A4 | |
| SCHEMBL4225172 | 0.86 | AQP1 (0.35) | AQP1BRD4MAPTALDH1A1CYP3A4 | |
| SCHEMBL4235890 | 0.86 | KMT2A (0.38) | AQP1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4234327 | 0.85 | AQP1 (0.48) | AQP1MAPTKMT2AALDH1A1CYP3A4 | |
| SCHEMBL4233775 | 0.85 | ALDH1A1 (0.37) | MAPTSMN1; SMN2ALDH1A1GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082434-A1 | Dihydrobenzofuranyl Alkanamine Derivatives and Methods for Using Same | WYETH (US) | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082434-A1 | Dihydrobenzofuranyl Alkanamine Derivatives and Methods for Using Same | HTR2C, HTR1A, HTR3A | AQP1 1105/4885S1PR4 490/4885S1PR2 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.