Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | AQP1 | P29972 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4225172 | 0.93 | AQP1 (0.35) | ALDH1A1MAPK14BRD4AQP1CYP3A4 | |
| SCHEMBL4231128 | 0.91 | ALDH1A1 (0.36) | ALDH1A1AQP1CYP3A4CYP2D6TSHR | |
| SCHEMBL4225277 | 0.91 | ALDH1A1 (0.36) | ALDH1A1BRD4CYP3A4CYP2D6TSHR | |
| SCHEMBL4225513 | 0.90 | AQP1 (0.37) | ALDH1A1AQP1CYP3A4CYP2D6TSHR | |
| SCHEMBL4219829 | 0.90 | AQP1 (0.37) | ALDH1A1BRD4AQP1CYP3A4CYP2D6 | |
| SCHEMBL4234479 | 0.89 | CYP3A4 (0.38) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL4230948 | 0.89 | AQP1 (0.47) | ALDH1A1AQP1CYP3A4CYP2D6TSHR | |
| SCHEMBL4226401 | 0.89 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP2D6TSHRL3MBTL1 | |
| SCHEMBL4232197 | 0.88 | HPRT1 (0.34) | ALDH1A1AQP1CYP3A4CYP2D6TSHR | |
| SCHEMBL4222464 | 0.87 | MAPT (0.34) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082434-A1 | Dihydrobenzofuranyl Alkanamine Derivatives and Methods for Using Same | WYETH (US) | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082434-A1 | Dihydrobenzofuranyl Alkanamine Derivatives and Methods for Using Same | HTR2C, HTR1A, HTR3A | ALDH1A1 190/4885MAPK14 2810/4885BRD4 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.