Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.51 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4218720 | 0.92 | ALDH1A1 (0.55) | ALDH1A1CYP2D6SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL4224621 | 0.88 | SIGMAR1 (0.53) | ALDH1A1SIGMAR1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL2996293 | 0.84 | CYP2D6 (0.68) | ALDH1A1CYP2D6KDM4EMAPTOPRM1 | |
| SCHEMBL20187124 | 0.83 | ALDH1A1 (0.58) | ALDH1A1CYP2D6SIGMAR1KDM4EPOLB | |
| SCHEMBL7707050 | 0.83 | ALDH1A1 (0.61) | ALDH1A1CYP2D6SMN1; SMN2KDM4ELMNA | |
| SCHEMBL20187134 | 0.83 | CYP2D6 (0.58) | ALDH1A1CYP2D6SIGMAR1MAPK1POLB | |
| SCHEMBL4213929 | 0.80 | SMN1; SMN2 (0.54) | ALDH1A1SIGMAR1SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL11564966 | 0.80 | NPFFR1 (0.64) | ALDH1A1CYP2D6SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL11566812 | 0.80 | UBE2M (0.57) | ALDH1A1CYP2D6SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL16876691 | 0.78 | CYP2D6 (0.58) | ALDH1A1CYP2D6SIGMAR1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090030041-A1 | N-substituted N-(4-piperidinyl) Amide Derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1795526-A1 | N-SUBSTITUTED N-(4-PIPERIDINYL)AMIDE DERIVATIVE | Nippon Chemiphar Co., Ltd. (JP) | 2007-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030041-A1 | N-substituted N-(4-piperidinyl) Amide Derivative | OPRM1, OPRD1, H1-0 | ALDH1A1 293/4885CYP2D6 1596/4885SIGMAR1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.