SCHEMBL42207

SCHEMBL42207

NC1CCN(Cc2ccccc2)CC1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.67
SIGMAR1 Q99720 3/20 0.65
CCR3 P51677 1/20 0.65
DRD2 P14416 3/20 0.61
DRD4 P21917 3/20 0.61
DRD3 P35462 3/20 0.61
BACE1 P56817 2/20 0.59
BCHE P06276 1/20 0.59
ALDH1A1 P00352 1/20 0.56
CXCR4 P61073 1/20 0.56
HTR2A P28223 1/20 0.56
MC4R P32245 1/20 0.55
LTA4H P09960 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2673764 0.98 ACHE (0.65) ACHESIGMAR1CCR3DRD2DRD4
Hydrochloric Acid SCHEMBL1624601 0.98 ACHE (0.65) ACHESIGMAR1CCR3DRD2DRD4
SCHEMBL1061618 0.93 ACHE (0.59) ACHESIGMAR1CCR3DRD2DRD4
Piperazine SCHEMBL3435125 0.91 SIGMAR1 (0.66) ACHESIGMAR1CCR3DRD2DRD4
Isopropylamine SCHEMBL7081467 0.91 ACHE (0.62) ACHESIGMAR1CCR3DRD2DRD4
SCHEMBL1206045 0.90 DRD2 (0.59) ACHESIGMAR1CCR3DRD2DRD4
SCHEMBL4951740 0.90 SIGMAR1 (0.64) ACHESIGMAR1CCR3DRD2DRD4
SCHEMBL239922 0.89 ACHE (0.58) ACHESIGMAR1CCR3DRD2DRD4
SCHEMBL42501 0.89 ACHE (0.58) ACHESIGMAR1CCR3DRD2DRD4
SCHEMBL330609 0.89 ACHE (0.58) ACHESIGMAR1CCR3DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3985 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528777-B2 Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2026-01-20 US claimed
WO-2025203062-A1 INDOLE-BASED SMALL MOLECULE ANTIVIRALS AGAINST SARS-COV-2 COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2025-10-02 WO claimed
US-12331193-B2 Hydrophobically modified alkylene oxide polymer mixture ROHM AND HAAS COMPANY (US) 2025-06-17 US claimed
EP-4058498-B1 HYDROPHOBICALLY MODIFIED ALKYLENE OXIDE POLYMER MIXTURE ROHM & HAAS (US) 2025-03-12 EP claimed
CN-118892484-A Application of 4-amino-1-benzyl piperidine in preparation of medicines for preventing and/or treating acute lung injury 中国医学科学院药物研究所 2024-11-05 CN claimed
CN-118892483-A Application of MPO enzyme inhibitor in preparation of medicine for preventing and/or treating neuroinflammatory diseases 中国医学科学院药物研究所 2024-11-05 CN claimed
CN-118812777-A Anhydride-containing sulfonyl/phosphonyl copolymer and preparation method and application thereof 四川大学 2024-10-22 CN claimed
CN-118459650-A Carboxyl-sulfonyl/phosphonyl-containing copolymer and preparation method and application thereof 四川大学 2024-08-09 CN claimed
CN-118067908-B Targeted data analysis method for non-targeted metabonomics research 长春中医药大学 2024-07-05 CN claimed
CN-115160300-B Coumarin compound, preparation method thereof and application of coumarin compound in resisting Alzheimer disease 中国人民解放军北部战区总医院 2024-05-31 CN claimed
WO-2001023392-A1 TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-04-05 WO claimed
EP-0667562-B1 Charge injection barrier for positive charging organic photoconductor HEWLETT PACKARD CO (US) 2001-03-21 EP claimed
WO-2000055120-A1 AMIDE DERIVATIVES ASTRAZENECA AB (SE) 2000-09-21 WO claimed
WO-2000044216-A1 GAMBOGIC ACID, ANALOGS AND DERIVATIVES AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS CYTOVIA, INC. (US) 2000-08-03 WO claimed
WO-2000018738-A1 BENZAMIDE DERIVATIVES AND THEIR USE AS CYTOKINE INHIBITORS ASTRAZENECA AB (SE) 2000-04-06 WO claimed
WO-2000007991-A1 AMIDE DERIVATIVES USEFUL AS INHIBITORS OF THE PRODUCTION OF CYTOKINES ASTRAZENECA AB (SE) 2000-02-17 WO claimed
US-5066643-A Enzyme inhibitors, protease and esterase, hypotensive agents, congestive heart failure SANDOZ LTD. (CH) 1991-11-19 US claimed
EP-0385044-A1 New piperidine derivatives as antihistaminics FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) 1990-09-05 EP claimed
US-4746649-A Diamino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1988-05-24 US claimed
EP-0186977-A2 Renin-inhibitory dipeptides, their preparation and use SANKYO COMPANY LIMITED (JP) 1986-07-09 EP claimed