Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 8/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205855 | 0.88 | TBXAS1 (0.46) | TBXAS1TBXA2RHDAC6 | |
| SCHEMBL27651289 | 0.73 | KCNN4 (0.46) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL5497374 | 0.69 | TBXAS1 (0.49) | TBXAS1TBXA2R | |
| SCHEMBL27884300 | 0.69 | HDAC3 (0.48) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL2922377 | 0.69 | LMNA (0.45) | MAPK1CES1KCNN4 | |
| SCHEMBL1051513 | 0.69 | CYP2C19 (0.57) | HDAC6HDAC3HDAC4HDAC1SMN1; SMN2 | |
| SCHEMBL5753278 | 0.68 | FFAR4 (0.50) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL11754754 | 0.68 | CYP2C19 (0.60) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL28393601 | 0.68 | ALDH1A1 (0.58) | HDAC6HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL16468009 | 0.67 | KIF11 (0.55) | HDAC6HDAC3MAPK1ADRA1AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | claimed |