Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12735861 | 0.89 | CA12 (0.55) | MAOBMAOAKDM1ACA12CA1 | |
| SCHEMBL4222616 | 0.82 | F10 (0.42) | MAOBMAOAKDM1ACA12CA1 | |
| SCHEMBL3075967 | 0.80 | LMNA (0.41) | HTR2AHTR2CKCNH2GBA1 | |
| SCHEMBL12735865 | 0.77 | HTR6 (0.52) | MAOBMAOASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12735859 | 0.75 | MAOB (0.50) | MAOBMAOAKCNH2 | |
| SCHEMBL12807946 | 0.75 | ACHE (0.42) | MAOBMAOAKDM1ACA12CA1 | |
| SCHEMBL12735867 | 0.75 | MMP1 (0.54) | MAOBMAOASLC6A4HTR2C | |
| Hydrochloric Acid SCHEMBL1532794 | 0.74 | MAOB (0.51) | MAOBMAOAKCNH2 | |
| SCHEMBL17803 | 0.74 | HTR2A (0.51) | HTR2AHTR2CKCNH2GBA1 | |
| SCHEMBL76993 | 0.74 | LMNA (0.61) | MAOBMAOACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-B1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-01 | — | — | EP | claimed |