Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | HCK | P08631 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12735861 | 0.82 | CA12 (0.55) | KDM1ACA12CA1CA2CA4 | |
| SCHEMBL4222612 | 0.82 | MAOB (0.43) | KDM1APRMT5CA12CA1CA2 | |
| SCHEMBL8461967 | 0.76 | GSTP1 (0.54) | SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL15474587 | 0.76 | ALOX5 (0.50) | SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL12735859 | 0.74 | MAOB (0.50) | MAOAMAOB | |
| SCHEMBL11013737 | 0.73 | CYP1A2 (0.56) | SLC6A2SLC6A3MAOB | |
| Hydrochloric Acid SCHEMBL1532794 | 0.73 | MAOB (0.51) | MAOAMAOB | |
| SCHEMBL12807946 | 0.72 | ACHE (0.42) | KDM1ACA12CA1CA2CA4 | |
| SCHEMBL12735867 | 0.72 | MMP1 (0.54) | SLC6A4MAOAMAOB | |
| SCHEMBL12735865 | 0.71 | HTR6 (0.52) | SLC6A2SLC6A4SLC6A3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-B1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-01 | — | — | EP | claimed |