Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NDUFS8 | O00217 | 3/20 | 0.45 |
| ▸ | COXFA4 | O00483 | 3/20 | 0.45 |
| ▸ | NDUFAB1 | O14561 | 3/20 | 0.45 |
| ▸ | NDUFA1 | O15239 | 3/20 | 0.45 |
| ▸ | NDUFS4 | O43181 | 3/20 | 0.45 |
| ▸ | NDUFB5 | O43674 | 3/20 | 0.45 |
| ▸ | NDUFB3 | O43676 | 3/20 | 0.45 |
| ▸ | NDUFC1 | O43677 | 3/20 | 0.45 |
| ▸ | NDUFA2 | O43678 | 3/20 | 0.45 |
| ▸ | NDUFS5 | O43920 | 3/20 | 0.45 |
| ▸ | NDUFS7 | O75251 | 3/20 | 0.45 |
| ▸ | NDUFS2 | O75306 | 3/20 | 0.45 |
| ▸ | NDUFS6 | O75380 | 3/20 | 0.45 |
| ▸ | NDUFB1 | O75438 | 3/20 | 0.45 |
| ▸ | NDUFS3 | O75489 | 3/20 | 0.45 |
| ▸ | NDUFB6 | O95139 | 3/20 | 0.45 |
| ▸ | NDUFA3 | O95167 | 3/20 | 0.45 |
| ▸ | NDUFB4 | O95168 | 3/20 | 0.45 |
| ▸ | NDUFB8 | O95169 | 3/20 | 0.45 |
| ▸ | NDUFB2 | O95178 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095793 | 0.86 | MAOA (0.47) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL19171940 | 0.86 | MAOA (0.47) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL592765 | 0.85 | AGER (0.54) | MAOBKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL28061786 | 0.83 | NDUFS8 (0.58) | NDUFS8COXFA4NDUFAB1NDUFA1NDUFS4 | |
| SCHEMBL2186487 | 0.79 | ALDH1A1 (0.52) | MAOAMAOBKDM4EALDH1A1KMT2A | |
| SCHEMBL9292707 | 0.79 | ALDH1A1 (0.52) | MAOAMAOBKDM4EALDH1A1KMT2A | |
| SCHEMBL2190565 | 0.79 | ALDH1A1 (0.52) | MAOAMAOBKDM4EALDH1A1KMT2A | |
| SCHEMBL1096028 | 0.79 | ALDH1A1 (0.52) | MAOAMAOBKDM4EALDH1A1KMT2A | |
| SCHEMBL3135327 | 0.79 | ALDH1A1 (0.52) | MAOAMAOBKDM4EALDH1A1KMT2A | |
| SCHEMBL592851 | 0.78 | ALDH1A1 (0.60) | MAOBKDM4EALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463728-B1 | FUSED CYCLIC MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2009-01-14 | — | — | EP | disclosed |