Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.46 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.46 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.46 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.46 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.46 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.46 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.46 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.46 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.46 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.46 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.46 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.46 |
| ▸ | NDUFS6 | O75380 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19171940 | 1.00 | MAOA (0.47) | MAOAMAOBALDH1A1KMT2AKDM4E | |
| SCHEMBL3135327 | 0.94 | ALDH1A1 (0.52) | MAOAMAOBALDH1A1KMT2AKDM4E | |
| SCHEMBL2186487 | 0.94 | ALDH1A1 (0.52) | MAOAMAOBALDH1A1KMT2AKDM4E | |
| SCHEMBL1096028 | 0.94 | ALDH1A1 (0.52) | MAOAMAOBALDH1A1KMT2AKDM4E | |
| SCHEMBL9292707 | 0.94 | ALDH1A1 (0.52) | MAOAMAOBALDH1A1KMT2AKDM4E | |
| SCHEMBL2190565 | 0.94 | ALDH1A1 (0.52) | MAOAMAOBALDH1A1KMT2AKDM4E | |
| SCHEMBL4223262 | 0.86 | NDUFS8 (0.45) | MAOAMAOBALDH1A1KMT2AKDM4E | |
| SCHEMBL28061786 | 0.86 | NDUFS8 (0.58) | MAOBALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL1526869 | 0.84 | KDM4E (0.63) | MAOBALDH1A1KMT2AKDM4EGLA | |
| SCHEMBL1095445 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KMT2AKDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328907-B1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP ASSETS BV (NL) | 2018-12-12 | — | — | EP | disclosed |
| US-20180057803-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP ASSETS B.V. (NL) | 2018-03-01 | — | — | US | disclosed |
| EP-2593078-B1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE AG (DE) | 2016-11-30 | — | — | EP | disclosed |
| US-20160108383-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DSM IP ASSETS B.V. (NL) | 2016-04-21 | — | — | US | disclosed |
| US-9238804-B2 | Hydrolases, nucleic acids encoding them and methods for making and using them | DSM IP ASSETS B.V. (NL) | 2016-01-19 | — | — | US | disclosed |
| US-9012497-B2 | Cyclohexyl carbamate compounds as active anti-cellulite ingredients | SYMRISE AG (DE) | 2015-04-21 | — | — | US | disclosed |
| EP-2329032-B1 | Methods using polypeptides having hydrolase activity | BUNGE OILS INC (US) | 2014-04-30 | — | — | EP | disclosed |
| US-8709775-B2 | Hydrolases, nucleic acids encoding them and methods for making and using them | DSM IP ASSETS B.V. (NL) | 2014-04-29 | — | — | US | disclosed |
| US-8633203-B2 | Use of pterocarpans as active anti-cellulite ingredients | SYMRISE AG (DE) | 2014-01-21 | — | — | US | disclosed |
| US-8541191-B2 | Hydrolases, nucleic acids encoding them and methods for biocatalytic synthesis of structured lipids | BUNGE OILS, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| EP-2329032-A2 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | Bunge Oils, Inc (US) | 2011-06-08 | — | — | EP | disclosed |
| EP-2328907-A2 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | Verenium Corporation (US) | 2011-06-08 | — | — | EP | disclosed |
| US-20110034486-A1 | USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE GMBH & CO., KG (DE) | 2011-02-10 | — | — | US | disclosed |
| WO-2010097479-A2 | CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE GMBH & CO. KG (DE) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010089421-A2 | MENTHYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE GMBH & CO. KG (DE) | 2010-08-12 | — | — | WO | disclosed |
| US-20100129882-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BUNGE OILS, INC. | 2010-05-27 | — | — | US | disclosed |
| WO-2010024924-A2 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BUNGE OILS, INC. (US) | 2010-03-04 | — | — | WO | disclosed |
| WO-2010025395-A2 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORPORATION (US) | 2010-03-04 | — | — | WO | disclosed |
| US-20100055085-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | VERENIUM CORPORATION (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100055234-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | BUNGE OILS, INC. | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057803-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | PNLIP, NOTUM, LIPC | MAOA 2538/4885MAOB 3094/4885ALDH1A1 4218/4885 |
| US-20110034486-A1 | USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS | FABP4, PLIN1, CPT1B | MAOA 2275/4885MAOB 1827/4885ALDH1A1 2907/4885 |
| US-20160108383-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | PNLIP, NOTUM, LIPC | MAOA 2538/4885MAOB 3094/4885ALDH1A1 4218/4885 |
| US-20100055085-A1 | HYDROLASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | PNLIP, NOTUM, LIPC | MAOA 2538/4885MAOB 3094/4885ALDH1A1 4218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.