Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.63 |
| ▸ | REN | P00797 | 13/20 | 0.61 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4223930 | 1.00 | CTSD (0.63) | CTSDRENCTSBCTSKMMP1 | |
| SCHEMBL4223937 | 1.00 | CTSD (0.63) | CTSDRENCTSBCTSKMMP1 | |
| SCHEMBL4223933 | 1.00 | CTSD (0.63) | CTSDRENCTSBCTSKMMP1 | |
| SCHEMBL14436099 | 0.92 | CTSD (0.58) | CTSDREN | |
| SCHEMBL22928874 | 0.91 | REN (0.71) | RENCTSBCTSKMMP1MMP2 | |
| SCHEMBL20669382 | 0.85 | CTSS (0.70) | RENCTSBCTSKMMP1 | |
| SCHEMBL22928872 | 0.84 | MMP1 (0.60) | RENMMP1MMP2MMP3 | |
| SCHEMBL6897460 | 0.84 | REN (0.73) | RENCTSBCTSKPSEN1PSEN2 | |
| SCHEMBL9101385 | 0.84 | REN (0.73) | RENCTSBCTSKPSEN1PSEN2 | |
| SCHEMBL3046634 | 0.84 | REN (0.73) | RENCTSBCTSKPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105091-A1 | Modified Amino Acids | TECHNISCHE UNIVERSITAT WIEN (AT) | 2009-04-23 | — | — | US | disclosed |
| EP-1826199-A1 | Modified amino acids | Technische Universität Wien (AT) | 2007-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105091-A1 | Modified Amino Acids | SLC1A2, NR1H4, OXGR1 | CTSD 4401/4885REN 243/4885CTSB 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.