Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468298 | 0.82 | LMNA (0.52) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10991862 | 0.80 | ALDH1A1 (0.65) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27462408 | 0.76 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10981584 | 0.75 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26624956 | 0.74 | GSTO1 (0.49) | TDP1GSTO1 | |
| SCHEMBL10980705 | 0.73 | ALDH1A1 (0.53) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2992708 | 0.73 | GSTO1 (0.54) | ALDH1A1MEN1KMT2AGSTO1HTT | |
| SCHEMBL20314806 | 0.73 | GSTO1 (0.48) | TDP1GSTO1LMNA | |
| SCHEMBL17666019 | 0.73 | BCL2A1 (0.56) | TDP1GSTO1HPGD | |
| SCHEMBL17666071 | 0.73 | PSMB5 (0.51) | ALDH1A1RAB9AKMT2ATDP1GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115616227-B | Use of indole-3-acryloylglycine detection reagent, and kit and system for diagnosis or auxiliary diagnosis of chronic obstructive disease | 四川大学华西医院 | 2023-05-16 | — | — | CN | claimed |
| CN-115616227-A | Application of indole-3-acryloylglycine detection reagent, kit and system for diagnosing or assisting in diagnosing chronic obstructive pulmonary disease | 四川大学华西医院 | 2023-01-17 | — | — | CN | claimed |
| CN-115616227-B | Use of indole-3-acryloylglycine detection reagent, and kit and system for diagnosis or auxiliary diagnosis of chronic obstructive disease | 四川大学华西医院 | 2023-05-16 | — | — | CN | disclosed |
| CN-115616227-B | Use of indole-3-acryloylglycine detection reagent, and kit and system for diagnosis or auxiliary diagnosis of chronic obstructive disease | 四川大学华西医院 | 2023-05-16 | — | — | CN | disclosed |
| CN-115616227-B | Use of indole-3-acryloylglycine detection reagent, and kit and system for diagnosis or auxiliary diagnosis of chronic obstructive disease | 四川大学华西医院 | 2023-05-16 | — | — | CN | disclosed |
| CN-115616227-A | Application of indole-3-acryloylglycine detection reagent, kit and system for diagnosing or assisting in diagnosing chronic obstructive pulmonary disease | 四川大学华西医院 | 2023-01-17 | — | — | CN | disclosed |
| CN-115616227-A | Application of indole-3-acryloylglycine detection reagent, kit and system for diagnosing or assisting in diagnosing chronic obstructive pulmonary disease | 四川大学华西医院 | 2023-01-17 | — | — | CN | disclosed |
| CN-115616227-A | Application of indole-3-acryloylglycine detection reagent, kit and system for diagnosing or assisting in diagnosing chronic obstructive pulmonary disease | 四川大学华西医院 | 2023-01-17 | — | — | CN | disclosed |
| US-20090028796-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090028796-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | IDO1, IDO2, INMT | ALDH1A1 2643/4885NPC1 4509/4885RAB9A 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.