Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.42 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.42 |
| ▸ | FGR | P09769 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658039 | 0.84 | MAPT (0.43) | ADORA2ACSNK1A1CSNK1DCSNK1G1FGR | |
| SCHEMBL28287515 | 0.79 | ADORA2A (0.58) | ADORA2ACSNK1A1CSNK1DCSNK1G1FGR | |
| Methylamine SCHEMBL10780560 | 0.78 | ADORA2A (0.56) | ADORA2ACSNK1A1CSNK1DCSNK1G1FGR | |
| SCHEMBL6390809 | 0.77 | P2RY4 (0.46) | MAPTSMN1; SMN2MAPK1RAB9APABPC1 | |
| SCHEMBL14582002 | 0.76 | POLB (0.56) | MAPTSMN1; SMN2MAPK1RAB9APABPC1 | |
| SCHEMBL29940221 | 0.75 | POLB (0.63) | MAOAMAPTSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL11131632 | 0.75 | POLB (0.63) | MAOAMAPTSMN1; SMN2MAPK1RAB9A | |
| SCHEMBL3168294 | 0.72 | MAPK1 (0.54) | ADORA2ACSNK1A1CSNK1DCSNK1G1FGR | |
| SCHEMBL27496947 | 0.72 | MAOA (0.53) | ADORA2ACSNK1A1CSNK1DCSNK1G1FGR | |
| SCHEMBL8997882 | 0.72 | ADORA2A (0.47) | ADORA2ACSNK1A1CSNK1DCSNK1G1FGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090068255-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | LIVING PROOF, INC. | 2009-03-12 | — | — | US | disclosed |
| US-5972044-A | Composition and method for dyeing keratin fibers | WELLA AG (DE) | 1999-10-26 | — | — | US | disclosed |
| US-4695653-A | Cationic surface-active agents | L'OREAL (FR) | 1987-09-22 | — | — | US | disclosed |
| US-4436909-A | HAIR COSMETICS | L'OREAL (FR) | 1984-03-13 | — | — | US | disclosed |
| US-4220602-A | FOR HAIR COSMETICS | L'OREAL (FR) | 1980-09-02 | — | — | US | disclosed |
| US-4096332-A | POLYHYDROXYLATED TERTIARY AMINES OR QUATERNARY AMMONIUM SALTS THEREOF | L'OREAL (FR) | 1978-06-20 | — | — | US | disclosed |
| US-4009255-A | POLYHYDROXYLATED TERTIARY AMINES | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-02-22 | — | — | US | disclosed |
| US-3960476-A | OXIDATION BASE | GHILARDI GIULIANA | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090068255-A1 | USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE | MMP1, MMP9, MMP17 | ADORA2A 3915/4885CSNK1A1 1089/4885CSNK1D 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.