Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R31 | P59538 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382209 | 0.82 | TUBB4A (0.47) | TAS2R31MAPTALDH1A1HPGDXDH | |
| SCHEMBL27775950 | 0.82 | ALDH1A1 (0.35) | TAS2R31MAPTALDH1A1HPGDPTPN1 | |
| SCHEMBL27775453 | 0.77 | NPC1 (0.44) | TAS2R31MAPTALDH1A1HPGDPTPN1 | |
| SCHEMBL8066879 | 0.74 | GSK3B (0.46) | TAS2R31MAPTALDH1A1HPGDXDH | |
| SCHEMBL29286026 | 0.73 | ALDH1A1 (0.38) | TAS2R31ALDH1A1HPGDABCB1XDH | |
| SCHEMBL782044 | 0.73 | TAS2R31 (0.74) | TAS2R31MAPTALDH1A1HPGDPTPN1 | |
| SCHEMBL4225984 | 0.73 | TAS2R31 (0.74) | TAS2R31MAPTALDH1A1HPGDPTPN1 | |
| SCHEMBL28403906 | 0.73 | ABCB1 (0.47) | MAPTALDH1A1ABCB1ABCG2KDM4E | |
| SCHEMBL7605697 | 0.72 | XDH (0.42) | TAS2R31ALDH1A1HPGDABCB1XDH | |
| SCHEMBL28552152 | 0.72 | NPC1 (0.55) | MAPTABCB1ABCG2POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270495-A1 | Inhibitors of Phosphodiesterase Types 1 To 5 Based on Dioclein, Floranol, and Analogs Thereof | UNIVERSIDADE FEDERAL DE MINAS GERAIS (BR) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270495-A1 | Inhibitors of Phosphodiesterase Types 1 To 5 Based on Dioclein, Floranol, and Analogs Thereof | PDE5A, PDE12, PDE2A | TAS2R31 3553/4885MAPT 3111/4885ALDH1A1 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.