Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PNLIP | P16233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226495 | 0.81 | LMNA (0.46) | LMNAL3MBTL1SMN1; SMN2BCL2L1MCL1 | |
| SCHEMBL28842084 | 0.78 | HDAC1 (0.49) | LMNASMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL4081368 | 0.76 | CCR2 (0.60) | CCR2KMT2AMEN1 | |
| SCHEMBL3049477 | 0.76 | CCR2 (0.62) | LMNAKDM4EALDH1A1CCR2PTGER4 | |
| SCHEMBL31090892 | 0.75 | PTGS1 (0.55) | LMNAL3MBTL1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3050565 | 0.75 | CCR2 (0.64) | LMNAKDM4EALDH1A1CCR2KMT2A | |
| SCHEMBL3274441 | 0.74 | CCR2 (0.50) | LMNABCL2L1MCL1KDM4EALDH1A1 | |
| SCHEMBL27716682 | 0.70 | L3MBTL1 (0.65) | LMNAL3MBTL1SMN1; SMN2ALDH1A1CACNA1H | |
| SCHEMBL11165536 | 0.70 | EPHX1 (0.60) | LMNAL3MBTL1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL680346 | 0.70 | SCN9A (0.57) | BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076491-A1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | Richter Gedeon NYRT (HU) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008068540-A1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2008-06-12 | — | — | WO | disclosed |