Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | BRD1 | O95696 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4226499 | 0.81 | LMNA (0.53) | LMNASMN1; SMN2L3MBTL1CCR2KDM4E | |
| SCHEMBL31090892 | 0.76 | PTGS1 (0.55) | LMNASMN1; SMN2L3MBTL1CCR2KDM4E | |
| SCHEMBL4081368 | 0.74 | CCR2 (0.60) | CCR2TRIM24BRD1BRPF1 | |
| SCHEMBL3049477 | 0.74 | CCR2 (0.62) | LMNACCR2KDM4EALDH1A1PTGER4 | |
| SCHEMBL3050565 | 0.73 | CCR2 (0.64) | LMNACCR2KDM4EALDH1A1FFAR1 | |
| SCHEMBL3274441 | 0.68 | CCR2 (0.50) | LMNACCR2KDM4EALDH1A1BCL2L1 | |
| SCHEMBL3039982 | 0.68 | CCR2 (0.58) | CCR2KDM4EPTGER4PTGER2 | |
| SCHEMBL1638973 | 0.68 | L3MBTL1 (0.57) | LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL3050790 | 0.68 | PTPN1 (0.61) | CCR2BCL2L1MCL1FFAR1FFAR4 | |
| SCHEMBL3982948 | 0.65 | MRGPRX1 (0.53) | LMNACCR2KDM4EALDH1A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2076491-A1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | Richter Gedeon NYRT (HU) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008068540-A1 | NEW BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2008-06-12 | — | — | WO | disclosed |