Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1789998 | 0.85 | PRKDC (0.37) | PRKDCKDM4EALDH1A1 | |
| SCHEMBL13219241 | 0.81 | HRH3 (0.33) | — | |
| SCHEMBL13219242 | 0.79 | PDK2 (0.33) | PDK2TP53 | |
| SCHEMBL2599682 | 0.76 | SMN1; SMN2 (0.37) | PRKDCPDK2MEN1KMT2AMAPT | |
| SCHEMBL13699530 | 0.76 | ALDH1A1 (0.36) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL13240239 | 0.75 | KIF11 (0.36) | PRKDCMEN1KMT2AMAPTTDP1 | |
| SCHEMBL13488507 | 0.75 | MAPT (0.35) | MEN1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL24620630 | 0.72 | PRKDC (0.35) | PRKDC | |
| SCHEMBL24659529 | 0.72 | PRKDC (0.35) | PRKDC | |
| SCHEMBL3034775 | 0.71 | HRH3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098520-A1 | Photochromic dichroic naphtho-pyrans and optical articles containing them | Essilor International (Compagnie Générale D'Optique) (FR) | 2009-09-09 | — | — | EP | claimed |
| EP-2098520-A1 | Photochromic dichroic naphtho-pyrans and optical articles containing them | Essilor International (Compagnie Générale D'Optique) (FR) | 2009-09-09 | — | — | EP | disclosed |
| EP-2098520-A1 | Photochromic dichroic naphtho-pyrans and optical articles containing them | Essilor International (Compagnie Générale D'Optique) (FR) | 2009-09-09 | — | — | EP | disclosed |