Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5467799 | 0.84 | CACNA2D1 (0.47) | CACNA2D1CACNA1BCACNB1CACNA1CRAB9A | |
| SCHEMBL5448603 | 0.83 | ALDH1A1 (0.47) | CACNA2D1CACNA1BCACNB1CACNA1CRAB9A | |
| SCHEMBL5467654 | 0.82 | MAPT (0.52) | RAB9AGFERALDH1A1KDM4ECASP1 | |
| SCHEMBL3478431 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KDM4ECASP1MEN1KMT2A | |
| SCHEMBL5460735 | 0.80 | CACNA2D1 (0.44) | CACNA2D1CACNA1BCACNB1CACNA1CRAB9A | |
| SCHEMBL5451862 | 0.80 | DRD2 (0.49) | CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1 | |
| SCHEMBL5461318 | 0.80 | MEN1 (0.55) | RAB9AGFERALDH1A1KDM4ECASP1 | |
| Hydrochloric Acid SCHEMBL7399479 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4ECASP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1374318 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4ECASP1MEN1KMT2A | |
| SCHEMBL7339023 | 0.77 | CACNA2D1 (0.65) | CACNA2D1CACNA1BCACNB1CACNA1CRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096104-A1 | Organic diamines as mGluR7 modulators | Novartis AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| US-20080242698-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242698-A1 | Organic Compounds | AOC1, OTC, ODC1 | CACNA2D1 1644/4885CACNA1B 2203/4885CACNB1 2610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.