Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18812586 | 0.90 | TDP1 (0.57) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL8095249 | 0.82 | MTOR (1.00) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL5093228 | 0.81 | TDP1 (0.48) | MTORRAB9AGRM7TSHRTDP1 | |
| SCHEMBL13184504 | 0.81 | TDP1 (0.54) | CYP3A4TDP1PKMKMT2AALDH1A1 | |
| SCHEMBL25791341 | 0.81 | TDP1 (0.54) | CYP3A4TDP1PKMKMT2AALDH1A1 | |
| SCHEMBL23349002 | 0.80 | LTA4H (0.58) | CYP3A4TDP1PKMKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3012657 | 0.80 | CYP3A4 (1.00) | MTORRAB9AGRM7CYP3A4ALOX15 | |
| SCHEMBL17340054 | 0.79 | TDP1 (0.53) | TDP1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL7780342 | 0.79 | KMT2A (0.54) | TDP1PKMKMT2AALDH1A1MITF | |
| SCHEMBL13164343 | 0.78 | ALDH1A1 (0.54) | CYP3A4TDP1PKMKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096104-A1 | Organic diamines as mGluR7 modulators | Novartis AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| US-20080242698-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242698-A1 | Organic Compounds | AOC1, OTC, ODC1 | MTOR 3816/4885RAB9A 4399/4885GRM7 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.