Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MET | P08581 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2149713 | 0.85 | MAPT (0.56) | MAPTALDH1A1NPSR1HPGDMET | |
| SCHEMBL3026762 | 0.85 | KMO (0.67) | MAPTALDH1A1NPSR1HPGDMET | |
| SCHEMBL8798927 | 0.82 | MET (0.57) | MAPTALDH1A1NPSR1HPGDMET | |
| SCHEMBL8798062 | 0.82 | ALDH1A1 (0.55) | MAPTALDH1A1NPSR1HPGDMET | |
| Hydrochloric Acid SCHEMBL9157992 | 0.81 | MET (0.56) | MAPTALDH1A1NPSR1HPGDMET | |
| SCHEMBL5717564 | 0.80 | MET (0.55) | MAPTALDH1A1NPSR1HPGDMET | |
| SCHEMBL21616847 | 0.80 | NPC1 (0.60) | ALDH1A1NPSR1HPGDSMN1; SMN2TP53 | |
| SCHEMBL2149119 | 0.78 | MIF (0.62) | MAPTALDH1A1NPSR1METSMN1; SMN2 | |
| SCHEMBL12124611 | 0.77 | SIGMAR1 (0.63) | MAPTMETKMOKMT2A | |
| SCHEMBL14199043 | 0.77 | POLB (0.52) | MAPTALDH1A1NPSR1HPGDMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | CEREP (FR) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233910-A1 | Npy antagonists, preparation and uses | NPY1R, NPY5R, NPY2R | MAPT 1398/4885ALDH1A1 4542/4885NPSR1 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.