Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4221953 | 0.71 | NOS3 (0.32) | NOS3NOS1 | |
| SCHEMBL10583880 | 0.65 | HRH3 (0.44) | NOS3NOS1ADORA2AADORA2B | |
| SCHEMBL17704768 | 0.65 | POLB (0.42) | — | |
| SCHEMBL28462842 | 0.64 | NOS1 (0.42) | NOS3NOS1 | |
| SCHEMBL29798830 | 0.62 | NOS3 (0.35) | NOS3NOS1ADORA2AADORA2B | |
| Hydrochloric Acid SCHEMBL28462844 | 0.62 | NOS1 (0.45) | NOS3NOS1ADORA2AADORA2B | |
| SCHEMBL20489211 | 0.59 | SLC18A3 (0.32) | ADORA2A | |
| SCHEMBL12389317 | 0.59 | ALDH1A1 (0.42) | NOS3NOS1ADORA2A | |
| SCHEMBL28358729 | 0.59 | NOS3 (0.41) | NOS3NOS1 | |
| SCHEMBL11515949 | 0.57 | POLB (0.44) | NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069569-A1 | CYCLOADDITION OF AZIDES AND ALKYNES | INSTITUT CATALA D'INVESTIGACIO QUIMICA (ES) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069569-A1 | CYCLOADDITION OF AZIDES AND ALKYNES | PF4, AFF4, FLI1 | NOS3 937/4885NOS1 1831/4885ADORA2A 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.