Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 8/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10098743 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL18671198 | 0.86 | SMN1; SMN2 (0.72) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL14191554 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL27913467 | 0.79 | MEN1 (0.89) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL23571724 | 0.78 | MEN1 (0.55) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL5052168 | 0.78 | NAAA (0.63) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL22430334 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL23571306 | 0.78 | L3MBTL1 (0.54) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL27603234 | 0.78 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL1959291 | 0.76 | SMN1; SMN2 (0.74) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009101016-A2 | MODIFIED HYBRID NANOPARTICLES | BASF SE (DE) | 2009-08-20 | — | — | WO | disclosed |