Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10098743 | 0.94 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL27913467 | 0.89 | MEN1 (0.89) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL14191554 | 0.89 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL27603234 | 0.88 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL4230630 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL14191558 | 0.85 | MEN1 (0.73) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL22938967 | 0.85 | MEN1 (0.81) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL23571724 | 0.84 | MEN1 (0.55) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL4743736 | 0.84 | MEN1 (0.80) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL39206 | 0.84 | KMT2A (1.00) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11234914-B2 | Monosubstituted urea derivatives as a self-tanning substance | MERCK PATENT GMBH (DE) | 2022-02-01 | — | — | US | disclosed |
| US-10893675-B2 | Powder formulation containing insect repellent | MERCK PATENT GMBH (DE) | 2021-01-19 | — | — | US | disclosed |
| US-20200038306-A1 | BARBITURIC ACID DERIVATIVES AS SELF-TANNING SUBSTANCES | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
| US-20200038304-A1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
| US-20190015307-A1 | INORGANIC PIGMENTS COMPOSED OF SPECIAL SPHERICAL COMPOSITE PARTICLES AS BOOSTER FOR SUN PROTECTION | MERCK PATENT GMBH (DE) | 2019-01-17 | — | — | US | disclosed |
| US-RE46698-E1 | Use of cyclohexanol derivatives as antimicrobial active compounds | MERCK PATENT GMBH (DE) | 2018-02-06 | — | — | US | disclosed |
| US-20180020661-A1 | POWDER FORMULATION CONTAINING INSECT REPELLENT | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20170304168-A1 | PHENYL KETONE DERIVATIVES AS SELF-TANNING AGENTS | MERCK PATENT GMBH (DE) | 2017-10-26 | — | — | US | disclosed |
| US-20170231889-A1 | Sunscreen Compositions Comprising Colour Pigments | BASF SE (DE) | 2017-08-17 | — | — | US | disclosed |
| US-9603784-B2 | Process for treating sol-gel capsules | MERCK PATENT GMBH (DE) | 2017-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180020661-A1 | POWDER FORMULATION CONTAINING INSECT REPELLENT | WAPL, ACHE, BPHL | SMN1; SMN2 3119/4885MEN1 50/4885KMT2A 699/4885 |
| US-11234914-B2 | Monosubstituted urea derivatives as a self-tanning substance | SLC14A1, TYR, UROD | SMN1; SMN2 4476/4885MEN1 1983/4885KMT2A 3385/4885 |
| US-20200038304-A1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | SLC14A1, TYR, UROD | SMN1; SMN2 4476/4885MEN1 1983/4885KMT2A 3385/4885 |
| US-20200038306-A1 | BARBITURIC ACID DERIVATIVES AS SELF-TANNING SUBSTANCES | TYR, SLC6A1, GABBR1 | SMN1; SMN2 4413/4885MEN1 2329/4885KMT2A 3301/4885 |
| US-20170231889-A1 | Sunscreen Compositions Comprising Colour Pigments | TYR, ERCC1, ERCC4 | SMN1; SMN2 3045/4885MEN1 1447/4885KMT2A 2807/4885 |
| US-10893675-B2 | Powder formulation containing insect repellent | WAPL, ACHE, BPHL | SMN1; SMN2 3119/4885MEN1 50/4885KMT2A 699/4885 |
| US-20170304168-A1 | PHENYL KETONE DERIVATIVES AS SELF-TANNING AGENTS | TYR, PAH, MITF | SMN1; SMN2 4778/4885MEN1 3472/4885KMT2A 1639/4885 |
| US-20190015307-A1 | INORGANIC PIGMENTS COMPOSED OF SPECIAL SPHERICAL COMPOSITE PARTICLES AS BOOSTER FOR SUN PROTECTION | RB1, TYR, XPO5 | SMN1; SMN2 2724/4885MEN1 714/4885KMT2A 3479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.