SCHEMBL10098743

SCHEMBL10098743

CCN(CC)c1ccc(C(=O)c2ccccc2C(=O)NCCCCCCNC(=O)c2ccccc2C(=O)c2ccc(N(CC)CC)cc2O)c(O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.67
▸ MEN1 O00255 1/20 0.67
▸ KMT2A Q03164 1/20 0.67
▸ L3MBTL1 Q9Y468 1/20 0.67
▸ KDM4E B2RXH2 1/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ POLB P06746 1/20 0.56
▸ GAA P10253 1/20 0.56
▸ NAAA Q02083 2/20 0.52
▸ APP P05067 9/20 0.50
▸ ALOX5 P09917 1/20 0.50
▸ TSHR P16473 1/20 0.49
▸ HTT P42858 1/20 0.49
▸ NPC1 O15118 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ RAB9A P51151 1/20 0.43
▸ NFKB2 Q00653 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14191554 0.94 SMN1; SMN2 (0.61) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL18671198 0.94 SMN1; SMN2 (0.72) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL23571306 0.89 L3MBTL1 (0.54) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL22430334 0.89 SMN1; SMN2 (0.54) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL23571724 0.88 MEN1 (0.55) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL4230630 0.87 SMN1; SMN2 (0.57) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL27913467 0.86 MEN1 (0.89) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL27603234 0.85 SMN1; SMN2 (0.66) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL14191558 0.82 MEN1 (0.73) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E
SCHEMBL22938967 0.82 MEN1 (0.81) SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023139038-A1 UV FILTER COMPOSITIONS COMPRISING HYBRID METAL OXIDE PARTICLES BASF SE (DE) 2023-07-27 — — WO disclosed
WO-2023139037-A1 UV FILTER COMPOSITIONS COMPRISING CLOSED-CELL METAL OXIDE PARTICLES BASF SE (DE) 2023-07-27 — — WO disclosed
US-20220183934-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES BASF SE (DE) 2022-06-16 — — US disclosed
WO-2020182936-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES BASF SE (DE) 2020-09-17 — — WO disclosed
EP-2994201-B1 COMPOSITIONS WITH HIGH QUANTITIES OF UV STABILIZERS BASF SE (DE) 2017-12-20 — — EP disclosed
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS BASF SE (DE) 2016-03-10 — — US disclosed
WO-2014180818-A1 AGENT CONTAINING LARGE QUANTITIES OF UV STABILIZERS BASF SE (DE) 2014-11-13 — — WO disclosed
US-8097240-B2 Use of transmission dyes for protecting human skin from browning and ageing BASF SE (DE) 2012-01-17 — — US disclosed
US-20100143274-A1 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS CIBA CORPORATION (US) 2010-06-10 — — US disclosed
US-20100143274-A1 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS CIBA CORPORATION (US) 2010-06-10 — — US disclosed
US-20090214453-A1 Use of Transmission Dyes for Protecting Human Skin From Browning and Ageing BASF SE (DE) 2009-08-27 — — US disclosed
US-20090214453-A1 Use of Transmission Dyes for Protecting Human Skin From Browning and Ageing BASF SE (DE) 2009-08-27 — — US disclosed
WO-2008107347-A2 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS BASF SE (CH) 2008-09-12 — — WO disclosed
US-7374749-B2 Amino substituted hydroxyphenyl benzophenone derivatives CIBA SPECIALTY CHEMICALS CORP. (US) 2008-05-20 — — US disclosed
US-7374749-B2 Amino substituted hydroxyphenyl benzophenone derivatives CIBA SPECIALTY CHEMICALS CORP. (US) 2008-05-20 — — US disclosed
WO-2007071584-A2 USE OF TRANSMISSION DYES FOR PROTECTING HUMAN SKIN FROM BROWNING AND AGEING CIBA HOLDING INC. (CH) 2007-06-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220183934-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES SDHB, SDHA, MCM5 SMN1; SMN2 3538/4885MEN1 759/4885KMT2A 2209/4885
US-20100143274-A1 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS MAOA, MAOB, ACMSD SMN1; SMN2 2903/4885MEN1 237/4885KMT2A 1439/4885
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS ERCC5, ERCC1, TTPA SMN1; SMN2 3653/4885MEN1 4242/4885KMT2A 3804/4885
US-20090214453-A1 Use of Transmission Dyes for Protecting Human Skin From Browning and Ageing CUTA, TYR, GLA SMN1; SMN2 1146/4885MEN1 1116/4885KMT2A 4124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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