SCHEMBL42319

SCHEMBL42319

Nc1nc2ncccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 2/20 1.00
METAP1 P53582 2/20 0.53
METAP2 P50579 1/20 0.53
MASP2 O00187 1/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
KMT2A Q03164 1/20 0.50
AOC3 Q16853 1/20 0.50
PDE5A O76074 2/20 0.49
FGFR1 P11362 1/20 0.48
FLT1 P17948 1/20 0.48
AURKA O14965 5/20 0.47
CDK5 Q00535 3/20 0.47
CDK5R1 Q15078 3/20 0.47
ULK1 O75385 1/20 0.47
CDK7 P50613 1/20 0.47
PRKCE Q02156 1/20 0.47
CAMK2G Q13555 1/20 0.47
DYRK1A Q13627 1/20 0.47
RPS6KA1 Q15418 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30413155 1.00 NUDT1 (1.00) NUDT1METAP1METAP2MASP2MEN1
Water SCHEMBL31266989 0.98 NUDT1 (0.96) NUDT1METAP1METAP2MASP2MEN1
Water SCHEMBL30578580 0.98 NUDT1 (0.96) NUDT1METAP1METAP2MASP2MEN1
Ammonia Solution, Strong SCHEMBL25287071 0.98 NUDT1 (0.96) NUDT1METAP1METAP2MASP2MEN1
SCHEMBL31042611 0.98 NUDT1 (0.96) NUDT1METAP1METAP2MASP2MEN1
SCHEMBL3997824 0.87 NUDT1 (0.75) NUDT1METAP1METAP2ALDH1A1KMT2A
SCHEMBL3998276 0.87 NUDT1 (0.75) NUDT1METAP1METAP2ALDH1A1KMT2A
SCHEMBL483317 0.80 NUDT1 (0.66) NUDT1MASP2MEN1ALDH1A1KMT2A
SCHEMBL30773469 0.80 NUDT1 (0.66) NUDT1MASP2MEN1ALDH1A1KMT2A
SCHEMBL1170747 0.78 METAP1 (0.72) NUDT1METAP1METAP2PDE5AFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 791 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12463229-B2 Bipolar ionomer membrane CAMX POWER LLC (US) 2025-11-04 US claimed
EP-3411430-B1 BIPOLAR IONOMER MEMBRANE CAMX POWER L L C (US) 2025-08-13 EP claimed
CN-108779275-B Bipolar ionomer membranes 坎麦克斯动力有限责任公司 2024-10-15 CN claimed
US-11773110-B2 Heterocycle amines and uses thereof LIGAND PHARMACEUTICALS INCORPORATED (US) 2023-10-03 US claimed
US-20230218521-A1 IMMUNOMODULATING TREATMENTS OF BODY CAVITIES UROGEN PHARMA LTD. (IL) 2023-07-13 US claimed
US-20220352534-A1 BIPOLAR IONOMER MEMBRANE CAMX POWER, L.L.C. 2022-11-03 US claimed
US-11417904-B2 Bipolar ionomer membrane CAMX POWER LLC (US) 2022-08-16 US claimed
US-20220119413-A1 HETEROCYCLE AMINES AND USES THEREOF CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2022-04-21 US claimed
US-10933129-B2 Methods for administering synthetic nanocarriers that generate humoral and cytotoxic T lymphocyte responses SELECTA BIOSCIENCES, INC. (US) 2021-03-02 US claimed
US-20200397695-A1 IMMUNOMODULATING TREATMENTS OF BODY CAVITIES UROGEN PHARMA LTD. (IL) 2020-12-24 US claimed
US-20030185835-A1 Adjuvant for vaccines POWDERJECT RESEARCH LIMITED (GB) 2003-10-02 US claimed
WO-2003080114-A2 IMIDAZOQUINOLINE ADJUVANTS FOR VACCINES POWDERMED LIMITED (GB) 2003-10-02 WO claimed
WO-2003080112-A2 IMIDAZOQUINOLINEAMINES AS ADJUVANTS IN HIV DNA VACCINATION POWDERMED LIMITED (GB) 2003-10-02 WO claimed
WO-2003072026-A2 METHOD OF REDUCING AND TREATING UVB-INDUCED IMMUNOSUPPRESSION 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-09-04 WO claimed
US-20030161797-A1 Method of reducing and treating UVB-induced immunosuppression 3M INNOVATIVE PROPERTIES COMPANY 2003-08-28 US claimed
CN-1437463-A System and method for treating a mucosal surface 3M INNOVATIVE PROPERTIES CO (US) 2003-08-20 CN claimed
WO-2003043572-A2 METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR PATHWAYS 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-05-30 WO claimed
EP-1221444-A1 FUSED IMIDAZOLE COMPOUNDS AND REMEDIES FOR DIABETES MELLITUS Eisai Co., Ltd. (JP) 2002-07-10 EP claimed
US-5023256-A Antihistamines DOMPE FARMACEUTICI S.P.A. (IT) 1991-06-11 US claimed
EP-0397613-A2 Pharmacologically active aminoimidazopyridines DOMPE' FARMACEUTICI S.p.A. (IT) 1990-11-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230218521-A1 IMMUNOMODULATING TREATMENTS OF BODY CAVITIES IL2, CD47, IFNG NUDT1 3813/4885METAP1 901/4885METAP2 668/4885
US-10933129-B2 Methods for administering synthetic nanocarriers that generate humoral and cytotoxic T lymphocyte responses CD4, CD47, GZMB NUDT1 2691/4885METAP1 2548/4885METAP2 2583/4885
US-11773110-B2 Heterocycle amines and uses thereof HNMT, NQO1, ACHE NUDT1 21/4885METAP1 2785/4885METAP2 1877/4885
US-20200397695-A1 IMMUNOMODULATING TREATMENTS OF BODY CAVITIES IL2, CD47, IFNG NUDT1 3813/4885METAP1 901/4885METAP2 668/4885
US-20030185835-A1 Adjuvant for vaccines TLR9, TLR3, TLR5 NUDT1 1234/4885METAP1 2619/4885METAP2 2218/4885
US-20220119413-A1 HETEROCYCLE AMINES AND USES THEREOF HNMT, NQO1, ACHE NUDT1 21/4885METAP1 2785/4885METAP2 1877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.