Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | PRKACA | P17612 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | PRKX | P51817 | 2/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13911549 | 1.00 | CHRM2 (0.46) | CHRM2CHRM1CHRM3MMP13ROCK1 | |
| SCHEMBL4235782 | 1.00 | CHRM2 (0.46) | CHRM2CHRM1CHRM3MMP13ROCK1 | |
| SCHEMBL4232995 | 0.94 | NAAA (0.47) | CHRM2CHRM1CHRM3MMP13ROCK1 | |
| SCHEMBL13911548 | 0.94 | NAAA (0.47) | CHRM2CHRM1CHRM3MMP13ROCK1 | |
| SCHEMBL4232993 | 0.94 | NAAA (0.47) | CHRM2CHRM1CHRM3MMP13ROCK1 | |
| SCHEMBL4232683 | 0.93 | OPRK1 (0.46) | CHRM2CHRM1CHRM3MMP13ROCK1 | |
| SCHEMBL13911552 | 0.93 | OPRK1 (0.46) | CHRM2CHRM1CHRM3MMP13ROCK1 | |
| SCHEMBL4232681 | 0.93 | OPRK1 (0.46) | CHRM2CHRM1CHRM3MMP13ROCK1 | |
| SCHEMBL4232899 | 0.88 | ROCK1 (0.46) | MMP13ROCK1PRKACACYP3A4CYP2C9 | |
| SCHEMBL4927015 | 0.88 | ROCK2 (0.57) | CHRM2CHRM1CHRM3MMP13ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076064-A1 | Compounds | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | US | claimed |
| US-20090076064-A1 | Compounds | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076064-A1 | Compounds | CEL, PLA2G2D, CCKBR | CHRM2 592/4885CHRM1 935/4885CHRM3 1512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.