SCHEMBL4236906

SCHEMBL4236906

O=C(O)c1ccc(CCN2CCC(N3CCCCC3)CC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 14/20 0.61
L3MBTL1 Q9Y468 11/20 0.61
MBTD1 Q05BQ5 5/20 0.59
TP53BP1 Q12888 2/20 0.59
MAPT P10636 1/20 0.51
HTR2A P28223 2/20 0.50
HTR2C P28335 1/20 0.50
HTR7 P34969 1/20 0.50
HTR6 P50406 1/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
MAPK1 P28482 1/20 0.50
KMT2A Q03164 1/20 0.50
HRH3 Q9Y5N1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22941361 0.86 L3MBTL3 (0.73) L3MBTL3L3MBTL1MBTD1TP53BP1KDM4E
SCHEMBL2741683 0.85 HRH3 (0.62) L3MBTL3L3MBTL1MBTD1HTR2AHTR2C
SCHEMBL7031548 0.85 HRH3 (0.62) L3MBTL3L3MBTL1MBTD1HTR2AHTR2C
Hydrochloric Acid SCHEMBL223935 0.84 HRH3 (0.61) L3MBTL3L3MBTL1MBTD1KMT2AHRH3
SCHEMBL7772142 0.84 SLC6A3 (0.61) L3MBTL3L3MBTL1MBTD1HTR2AHTR2C
Hydrochloric Acid SCHEMBL7447525 0.82 SLC6A3 (0.59) L3MBTL3L3MBTL1MBTD1HTR2AHTR2C
SCHEMBL27872811 0.80 SPHK1 (0.57) HTR2AHTR2CHTR7HTR6HRH3
SCHEMBL27805513 0.80 HRH3 (0.54) HTR2AHTR2CHTR7HTR6HRH3
SCHEMBL14320557 0.79 L3MBTL3 (0.67) L3MBTL3L3MBTL1MBTD1TP53BP1MAPT
SCHEMBL22386773 0.77 LTA4H (0.59) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090233910-A1 Npy antagonists, preparation and uses CEREP (FR) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090233910-A1 Npy antagonists, preparation and uses NPY1R, NPY5R, NPY2R L3MBTL3 4694/4885L3MBTL1 4663/4885MBTD1 3535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.