Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | PDE5A | O76074 | 1/20 | 0.53 |
| ▸ | PDE1A | P54750 | 1/20 | 0.53 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056618 | 0.89 | TUBB4A (0.58) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL4064802 | 0.84 | CCR4 (0.58) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL4239559 | 0.83 | PLAU (0.52) | MAPTALDH1A1GAAHPGDKMT2A | |
| SCHEMBL4241367 | 0.83 | AMY1A (0.62) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL4239615 | 0.83 | PLAU (0.44) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL4233688 | 0.80 | MEN1 (0.50) | MAPTALDH1A1GAAHPGDKMT2A | |
| SCHEMBL4240363 | 0.80 | CCR4 (0.42) | MAPTALDH1A1GAAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6930064 | 0.79 | PTGS2 (0.46) | MAPTALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL4065329 | 0.79 | PKM (0.47) | MAPTALDH1A1GAAHPGDKMT2A | |
| SCHEMBL4234726 | 0.79 | CCR4 (0.42) | MAPTALDH1A1GAAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010871-A2 | PYRAZOLE DERIVATIVES AS ANTAGONISTS OF ADENOSINE A3 RECEPTOR | ADDEX PHARMA S.A. (CH) | 2009-01-22 | — | — | WO | disclosed |