SCHEMBL4240713

SCHEMBL4240713

Cc1ccc(S(=O)(=O)O)c(CCBr)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.37
HSD17B10 Q99714 2/20 0.37
AMY1A P0DUB6 1/20 0.36
GSK3B P49841 1/20 0.35
ALDH1A1 P00352 3/20 0.35
POLB P06746 2/20 0.35
RECQL P46063 2/20 0.35
MEP1B Q16820 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
CASP6 P55212 1/20 0.35
ELAVL1 Q15717 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
MYC P01106 1/20 0.34
RAPGEF4 Q8WZA2 1/20 0.34
MPL P40238 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1180196 0.89 GAA (0.41) GAAHSD17B10AMY1AALDH1A1POLB
SCHEMBL30823619 0.89 GAA (0.41) GAAHSD17B10AMY1AALDH1A1POLB
SCHEMBL10817238 0.89 GAA (0.35) GAAHSD17B10AMY1AGSK3BALDH1A1
SCHEMBL29975298 0.86 GAA (0.39) GAAHSD17B10AMY1AALDH1A1POLB
SCHEMBL30723203 0.86 GAA (0.39) GAAHSD17B10AMY1AALDH1A1POLB
SCHEMBL5718625 0.86 GAA (0.39) GAAHSD17B10AMY1AALDH1A1POLB
SCHEMBL816601 0.86 GAA (0.39) GAAHSD17B10AMY1AALDH1A1POLB
SCHEMBL30716894 0.85 AMY1A (0.44) GAAHSD17B10AMY1AALDH1A1POLB
SCHEMBL14991279 0.85 AMY1A (0.44) GAAHSD17B10AMY1AALDH1A1POLB
SCHEMBL8084853 0.84 GAA (0.38) GAAHSD17B10AMY1AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674839-A1 NOVEL INDOLINE DERIVATIVE AND USE THEREOF CK Regeon Inc. (KR) 2026-01-07 EP disclosed
WO-2024181799-A1 NOVEL INDOLINE DERIVATIVE AND USE THEREOF 주식회사 씨케이리제온 2024-09-06 WO disclosed
CN-118284597-A Substituted indole compounds and uses thereof 特罗彼奥治疗私人有限公司 2024-07-02 CN disclosed
EP-3169666-B1 SUBSTITUTED AZASPIRO(4.5)DECANE DERIVATIVES GRUENENTHAL GMBH (DE) 2018-06-06 EP disclosed
US-20170210734-A1 Substituted Azaspiro(4.5)Decane Derivatives GRUENENTHAL GMBH (DE) 2017-07-27 US disclosed
EP-3169666-A1 SUBSTITUTED AZASPIRO(4.5)DECANE DERIVATIVES Grünenthal GmbH (DE) 2017-05-24 EP disclosed
WO-2016008582-A1 SUBSTITUTED AZASPIRO(4.5)DECANE DERIVATIVES Grünenthal GmbH (DE) 2016-01-21 WO disclosed
WO-2014098593-A9 VERAPAMIL LIKE COMPOUNDS STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2014-10-23 WO disclosed
WO-2014098593-A1 VERAPAMIL LIKE COMPOUNDS STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2014-06-26 WO disclosed
US-20130137625-A1 Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof SOLARBRE, INC. (US) 2013-05-30 US disclosed
US-8246869-B2 Photo-responsive microencapsulation materials, compositions and methods of use thereof SOLARBRE, INC. (US) 2012-08-21 US disclosed
US-20090202652-A1 Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof SOLARBRE, INC. (US) 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090202652-A1 Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof LIPA, LIPE, CRYAA GAA 134/4885HSD17B10 3865/4885AMY1A 1235/4885
US-20170210734-A1 Substituted Azaspiro(4.5)Decane Derivatives OPRL1, OPRM1, OPRD1 GAA 4141/4885HSD17B10 3382/4885AMY1A 4478/4885
US-20130137625-A1 Photo-Responsive Microencapsulation Materials, Compositions and Methods of Use Thereof LIPA, LIPE, CRYAA GAA 134/4885HSD17B10 3865/4885AMY1A 1235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.